Hsueh Er-Jung, Loh El-Wui, Lin Joyce Jui-An, Tam Ka-Wai
Cancer Center, Yuan's General Hospital, Kaohsiung, Taiwan.
Cochrane Taiwan, Taipei Medical University, Taipei, Taiwan.
Breast Cancer. 2021 Mar;28(2):264-276. doi: 10.1007/s12282-020-01209-6. Epub 2021 Jan 15.
Complications of breast cancer treatment can cause physical and psychosocial distress in patients. Yoga demonstrates substantial potential as a supportive therapy for patients with breast cancer. Our aim is to conduct a meta-analysis of randomized controlled trials to evaluate the effectiveness of yoga in enhancing the quality of life (QoL) of patients with breast cancer.
We searched for studies published before March 2020 in the PubMed, Embase, and Cochrane Library databases. Individual effect sizes were standardized, and the pooled effect size was calculated using a random effect model. Measured outcomes included QoL, anxiety and depression, stress, fatigue, pain severity, and sleep quality.
In total, 26 trials involving 2069 patients were reviewed. Significant enhancement in QoL was observed immediately after the yoga intervention. The pooled mean differences in social (weighted mean difference [WMD]: 1.36, 95% confidence interval [CI] 0.12-2.61), emotional (WMD: 1.46, 95% CI 0.26-2.66), and functional well-being (WMD: 2.04, 95% CI 0.21-3.87) were significantly higher in the yoga group than in the control group. Patients practicing yoga exhibited significant improvements in physical well-being, mental well-being, and sleep quality as well as reductions in anxiety, depression, stress, fatigue, and pain severity after the intervention.
Yoga may enhance QoL in patients with breast cancer experiencing post-treatment complications. Therefore, we recommend yoga as a supportive therapy for patients with breast cancer to relieve post-treatment distress.
乳腺癌治疗的并发症会给患者带来身体和心理社会困扰。瑜伽作为一种对乳腺癌患者的支持性疗法具有很大潜力。我们的目的是对随机对照试验进行荟萃分析，以评估瑜伽在提高乳腺癌患者生活质量（QoL）方面的有效性。
我们检索了2020年3月之前在PubMed、Embase和Cochrane图书馆数据库中发表的研究。对个体效应量进行标准化，并使用随机效应模型计算合并效应量。测量的结果包括生活质量、焦虑和抑郁、压力、疲劳、疼痛严重程度和睡眠质量。
总共审查了26项涉及2069名患者的试验。在瑜伽干预后立即观察到生活质量有显著提高。瑜伽组在社会（加权平均差[WMD]：1.36，95%置信区间[CI]0.12 - 2.61）、情感（WMD：1.46，95%CI 0.26 - 2.66）和功能幸福感（WMD：2.04，95%CI 0.21 - 3.87）方面的合并平均差显著高于对照组。干预后，练习瑜伽的患者在身体幸福感、心理幸福感和睡眠质量方面有显著改善，同时焦虑、抑郁、压力、疲劳和疼痛严重程度有所降低。
瑜伽可能会提高患有治疗后并发症的乳腺癌患者的生活质量。因此，我们建议将瑜伽作为乳腺癌患者的一种支持性疗法，以缓解治疗后的困扰。
