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COVID-19 诊断挑战:血液透析患者病例报告及文献复习。

Challenge in diagnosis of COVID-19 in hemodialysis patient: a case report and brief review of the literature.

机构信息

Division of Nephrology and Hypertension, Department of Internal Medicine, Faculty of Medicine, Universitas Padjadjaran/Hasan Sadikin General Hospital, Bandung, Indonesia.

Division of Infectious Disease and Tropical Medicine, Department of Internal Medicine, Faculty of Medicine, Universitas Padjadjaran/Hasan Sadikin General Hospital, Bandung, Indonesia.

出版信息

CEN Case Rep. 2021 Aug;10(3):341-347. doi: 10.1007/s13730-020-00571-w. Epub 2021 Jan 16.

Abstract

Diagnosis of COVID-19 in end-stage kidney disease (ESKD) patients on hemodialysis is challenging,  as the symptoms are often atypical. Herein, we reported a confimed case of COVID-19 in a patient on maintenance hemodialysis. A 38-year-old man with ESKD on regular hemodialysis initially presented with progressive shortness of breath and dry cough, without fever. He had lymphopenia, and chest X-ray suggested pulmonary edema with cardiomegaly and suspected bilateral bronchopneumonia. The patient clinically improved after 7 days of hospitalization, and was subsequently discharged from hospital. Ten days after being discharged, the patient was re-admitted with progressive shortness of breath and dry cough, without fever. SARS-CoV-2 infection was later confirmed by a qualitative RT-PCR test and the diagnosis COVID-19 pneumonia was established. We presented a case of atypical presentation of COVID-19 in an ESKD patient on maintenance hemodialysis with a brief review of the current literature.

摘要

终末期肾脏病(ESKD)患者在血液透析期间的 COVID-19 诊断具有挑战性,因为其症状通常不典型。在此,我们报告了 1 例维持性血液透析患者确诊的 COVID-19 病例。1 名 38 岁男性,患有 ESKD 且定期进行血液透析,最初表现为进行性呼吸急促和干咳,无发热。他出现淋巴细胞减少,胸部 X 线片提示肺水肿合并心脏扩大和疑似双侧支气管肺炎。患者住院 7 天后临床症状改善,随后出院。出院 10 天后,患者因进行性呼吸急促和干咳再次入院,无发热。随后通过定性 RT-PCR 检测证实 SARS-CoV-2 感染,诊断为 COVID-19 肺炎。我们报告了 1 例维持性血液透析的 ESKD 患者不典型的 COVID-19 表现,并对当前文献进行了简要回顾。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/50de/8271049/6086bebe2fca/13730_2020_571_Fig1_HTML.jpg

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