MSk Lab, Imperial College London, Sir Michael Uren Biomedical Engineering Research Hub, London, United Kingdom.
Department of Orthopaedics, Imperial College Healthcare NHS Trust, Charing Cross Hospital, London, United Kingdom.
Arthroscopy. 2021 May;37(5):1599-1609. doi: 10.1016/j.arthro.2020.12.235. Epub 2021 Jan 13.
To examine the relationship between posterior tibial slope and lateral meniscal bone angle (LMBA) on anterior cruciate ligament (ACL) tear risk in a pediatric population.
In this case-control study, non-contact ACL-injured pediatric patients with no significant lateral meniscal lesions were matched by age and sex in a 1:1 ratio to a group of radiologically normal controls. Knee magnetic resonance imaging (MRI) studies were analyzed by 3 independent, blinded observers measuring the medial posterior tibial slope (MTS), lateral posterior tibial slope (LTS), and LMBA. Sagittal slope asymmetry was calculated as the absolute difference in degrees between slopes, and the relationship between LMBA and LTS was calculated as a ratio. Binary logistic regressions identified independent predictors of ACL injury. Receiver operator characteristics were performed to determine predictive accuracy.
20 study patients were compared with 20 sex- and age-matched controls (age 14.8 ± 2.42, mean ± standard deviation). LTS was significantly higher in the ACL-injured group (11.30° ± 3.52° versus 7.00° ± 2.63°, P = .0001), as were the absolute slope difference (7.10 ± 2.92° versus 3.14 ± 3.25°, P = .0002) and LTS:LMBA ratio (0.46 ± 0.17 versus 0.26 ± 0.12, P = .0001). No significant differences were observed for MTS or LMBA. Independent predictors were LTS (odds ratio [OR] 1.58, 95% confidence interval [CI] 1.18 to 2.13, P = .002), LTS:LMBA ratio (OR 3.13, 95% CI 1.48 to 6.62, P = .003), and absolute slope difference (OR 1.65, 95% CI 1.17 to 2.32, P = .005). LTS:LMBA ratio was the strongest predictor variable (area under the curve 0.86).
This study suggests that LTS, absolute slope difference, and LTS:LMBA ratio are significant pediatric ACL-injury risk factors. All 3 demonstrate good predictive accuracy; however, the relationship between steep LTS and shallow LMBA was the strongest predictor.
III, case-control study.
在儿童人群中,研究胫骨后倾角(PTB)与外侧半月板骨角(LMBA)之间的关系,以探讨其与前交叉韧带(ACL)撕裂风险的关系。
在这项病例对照研究中,将无明显外侧半月板病变的非接触性 ACL 损伤的儿科患者与一组影像学正常的对照组按年龄和性别 1:1 配对。通过 3 位独立的、盲法观察者对内侧胫骨后倾角(MTS)、外侧胫骨后倾角(LTS)和 LMBA 进行膝关节磁共振成像(MRI)分析。矢状面斜率不对称性定义为斜率之间的绝对差值,LTS 与 LMBA 之间的关系定义为比值。二项逻辑回归确定 ACL 损伤的独立预测因子。接受者操作特征(ROC)曲线分析用于确定预测准确性。
共比较了 20 例 ACL 损伤患者和 20 例性别、年龄匹配的对照组(年龄 14.8 ± 2.42 岁,均数 ± 标准差)。ACL 损伤组的 LTS 明显较高(11.30° ± 3.52°对 7.00° ± 2.63°,P =.0001),斜率差异绝对值(7.10 ± 2.92°对 3.14 ± 3.25°,P =.0002)和 LTS:LMBA 比值(0.46 ± 0.17 对 0.26 ± 0.12,P =.0001)也较高。MTS 或 LMBA 无显著差异。独立预测因子为 LTS(比值比 [OR] 1.58,95%置信区间 [CI] 1.18 至 2.13,P =.002)、LTS:LMBA 比值(OR 3.13,95%CI 1.48 至 6.62,P =.003)和绝对斜率差(OR 1.65,95%CI 1.17 至 2.32,P =.005)。LTS:LMBA 比值是最强的预测变量(曲线下面积 0.86)。
本研究表明,LTS、绝对斜率差和 LTS:LMBA 比值是儿童 ACL 损伤的重要危险因素。这 3 项均具有良好的预测准确性;然而,陡峭的 LTS 与浅的 LMBA 之间的关系是最强的预测指标。
III 级,病例对照研究。