颈上神经节在松果体II型甲状腺素5'-脱碘酶活性夜间升高过程中的作用。
The role of the superior cervical ganglia in the nocturnal rise of pineal type-II thyroxine 5'-deiodinase activity.
作者信息
Murakami M, Greer M A, Hjulstad S, Greer S E, Tanaka K
机构信息
Department of Medicine, Oregon Health Sciences University, Portland 97201.
出版信息
Brain Res. 1988 Jan 12;438(1-2):366-8. doi: 10.1016/0006-8993(88)91365-0.
Superior cervical ganglionectomy (SCGx) abolished the nocturnal rise in pineal type-II thyroxine 5'-deiodinase (5'-D) activity in both euthyroid and hypothyroid rats. Isoproterenol induced at least as great a rise in diurnal pineal 5'-D in SCGx as in intact rats. These data suggest that beta-adrenergic stimulation through the superior cervical ganglia is essential for the nocturnal rise in pineal 5'-D activity.
切除双侧颈上神经节（SCGx）可消除正常甲状腺功能和甲状腺功能减退大鼠松果体II型甲状腺素5'-脱碘酶（5'-D）活性的夜间升高。异丙肾上腺素诱导SCGx大鼠松果体5'-D的昼夜升高幅度至少与完整大鼠一样大。这些数据表明，通过颈上神经节的β-肾上腺素能刺激对于松果体5'-D活性的夜间升高至关重要。
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