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抗病毒纳米结构表面降低 SARS-CoV-2 的存活能力。

Antiviral Nanostructured Surfaces Reduce the Viability of SARS-CoV-2.

机构信息

Centre for Biomedical Technologies, Science and Engineering Faculty, Queensland University of Technology, Brisbane, Queensland 4000, Australia.

Public Health Virology Laboratory, Forensic and Scientific Services, Coopers Plains, Queensland 4108, Australia.

出版信息

ACS Biomater Sci Eng. 2020 Sep 14;6(9):4858-4861. doi: 10.1021/acsbiomaterials.0c01091. Epub 2020 Sep 2.

DOI:10.1021/acsbiomaterials.0c01091
PMID:33455218
Abstract

In this letter, we report the ability of the nanostructured aluminum Al 6063 alloy surfaces to inactivate the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). There was no recoverable viable virus after 6 h of exposure to the nanostructured surface, elucidating a 5-log reduction compared to a flat Al 6063 surface. The nanostructured surfaces were fabricated using wet-etching techniques which generated nanotextured, randomly aligned ridges approximately 23 nm wide on the Al 6063 alloy surfaces. In addition to the excellent mechanical resilience properties previously shown, the etched surfaces have also demonstrated superior corrosion resistance compared to the control surfaces. Such nanostructured surfaces have the potential to be used in healthcare environment such as hospitals and public spaces to reduce the surface transmission of SARS-CoV-2 and combat COVID-19.

摘要

在这封信中,我们报告了纳米结构化铝 6063 合金表面使严重急性呼吸综合征冠状病毒 2(SARS-CoV-2)失活的能力。暴露于纳米结构化表面 6 小时后,没有可回收的存活病毒,与平面铝 6063 表面相比,减少了 5 个对数级。纳米结构化表面是使用湿法刻蚀技术制造的,该技术在铝 6063 合金表面上生成了约 23nm 宽的纳米结构化、随机排列的脊。除了先前显示的优异的机械弹性性能外,与对照表面相比,蚀刻表面还表现出优异的耐腐蚀性。这种纳米结构化表面有可能在医疗保健环境(如医院和公共场所)中使用,以减少 SARS-CoV-2 的表面传播并对抗 COVID-19。

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