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膀胱癌免疫治疗后的播散性感染和脊椎骨髓炎

Disseminated Infection and Vertebral Osteomyelitis following Immunotherapy for Bladder Cancer.

作者信息

Gill Harpreet S, Dasari Suhas P, Pandit Sarbagya, Ritter Thomas E, Raju Sushma B, Chartier Alexander R, Jha Pinky

机构信息

Department of Internal Medicine, Medical College of Wisconsin, Wauwatosa, Wisconsin, USA.

出版信息

Case Rep Infect Dis. 2020 Dec 28;2020:6676163. doi: 10.1155/2020/6676163. eCollection 2020.

DOI:10.1155/2020/6676163
PMID:33457027
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7785387/
Abstract

The use of BCG in immunotherapy for bladder cancer has been in practice for over 40 years. However, uncommon, serious complications can occur with the therapy. Here, we present a case of vertebral osteomyelitis secondary to dissemination of BCG following immunotherapy, an exceedingly rare presentation of an already rare complication.

摘要

卡介苗用于膀胱癌免疫治疗已有40多年的实践历史。然而，这种治疗可能会出现罕见的严重并发症。在此，我们报告一例免疫治疗后卡介苗播散继发椎体骨髓炎的病例，这是一种极为罕见的并发症的罕见表现。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ad08/7785387/771772f49b86/CRIID2020-6676163.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ad08/7785387/771772f49b86/CRIID2020-6676163.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ad08/7785387/771772f49b86/CRIID2020-6676163.001.jpg

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BCG-induced discitis and osteomyelitis in a patient with a history of bladder cancer.
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Bacillus Calmette-Guérin Cases Reported to the National Tuberculosis Surveillance System, United States, 2004-2015.国家结核病监测系统报告的卡介苗接种相关病例，美国，2004-2015 年。
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Human Tuberculosis Caused by Mycobacterium bovis in the United States, 2006-2013.2006-2013 年美国由牛分枝杆菌引起的人结核病。
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Mycobacterial Osteomyelitis of the Spine Following Intravesical BCG Therapy for Bladder Cancer.膀胱癌膀胱内卡介苗治疗后脊柱分枝杆菌性骨髓炎
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Recombinant Mycobacterium bovis BCG for immunotherapy in nonmuscle invasive bladder cancer.用于非肌肉浸润性膀胱癌免疫治疗的重组牛分枝杆菌卡介苗
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Bacillus Calmette-Guérin (BCG) infection following intravesical BCG administration as adjunctive therapy for bladder cancer: incidence, risk factors, and outcome in a single-institution series and review of the literature.卡介苗（BCG）膀胱内灌注作为膀胱癌辅助治疗后的感染：单中心系列研究中的发病率、危险因素及结局，并对文献进行综述
Medicine (Baltimore). 2014 Oct;93(17):236-254. doi: 10.1097/MD.0000000000000119.
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Mycobacterium bovis vertebral osteomyelitis as a complication of intravesical BCG use.牛分枝杆菌性脊椎骨髓炎作为膀胱内使用卡介苗的一种并发症。
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8
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