• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

6例青少年膝关节软骨碎片采用自体骨栓固定后的临床及影像学结果

Clinical and Radiographic Outcomes After Fixation of Chondral Fragments of the Knee in 6 Adolescents Using Autologous Bone Pegs.

作者信息

Ogura Takahiro, Sakai Hiroki, Asai Shigehiro, Fukuda Hideaki, Takahashi Tatsuya, Kanisawa Izumi, Yamaura Ichiro, Tsuchiya Akihiro, Forney Michael, Winalski Carl S, Takahashi Kenji

机构信息

Sports Medicine and Joint Center, Funabashi Orthopaedic Hospital, Funabashi, Chiba, Japan.

Imaging Institute, Cleveland Clinic, Cleveland, Ohio, USA.

出版信息

Orthop J Sports Med. 2020 Nov 17;8(11):2325967120963050. doi: 10.1177/2325967120963050. eCollection 2020 Nov.

DOI:10.1177/2325967120963050
PMID:33457431
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7787012/
Abstract

BACKGROUND

Little is known regarding the optimal treatment for displaced, purely chondral fragments in the knee.

PURPOSE

To report the clinical and radiographic outcomes of chondral fragment fixation in adolescents through use of autologous bone pegs.

STUDY DESIGN

Case series; Level of evidence, 4.

METHODS

This retrospective, single-center study evaluated 6 patients (mean age, 12.9 years) who underwent fixation of chondral fragments (no visualized bone attached) using autologous bone pegs (mean postoperative follow-up, 5.2 years; range, 1.4-10.9 years). The causes were trauma (n = 5) and osteochondritis dissecans (n = 1). Lesions were located in the trochlear groove (lateral, n = 3; medial, n = 2) or posterior part of the lateral femoral condyle (n = 1). The mean lesion size was 3.8 cm (range, 0.8-9.0 cm). Patients were evaluated via physical examination and magnetic resonance imaging (MRI) using magnetic resonance observation of cartilage repair tissue scores.

RESULTS

In total, 5 patients successfully returned to sports without restrictions at a mean of 7 months (range, 6-8 months) postoperatively. At the latest follow-up, these 5 patients had full range of motion and no joint effusion. The mean magnetic resonance observation of cartilage repair tissue score was 85 (range, 70-95) at a mean duration of 3 years (range, 1-5 years). One patient experienced failure at 1.3 years postoperatively after a traumatic injury and subsequently underwent removal of the fixed fragment and a drilling procedure.

CONCLUSION

In most adolescents, fixation of chondral fragments with no visualized bony portion using autologous bone pegs provided a satisfactory success rate and good healing of cartilage tissue confirmed on MRI scans.

摘要

背景

对于膝关节移位的单纯软骨碎片的最佳治疗方法,人们了解甚少。

目的

报告青少年使用自体骨栓固定软骨碎片的临床和影像学结果。

研究设计

病例系列;证据等级,4级。

方法

这项回顾性单中心研究评估了6例患者(平均年龄12.9岁),他们使用自体骨栓固定软骨碎片(未见附着骨)(平均术后随访5.2年;范围1.4 - 10.9年)。病因包括创伤(n = 5)和剥脱性骨软骨炎(n = 1)。病变位于滑车沟(外侧,n = 3;内侧,n = 2)或股骨外侧髁后部(n = 1)。平均病变大小为3.8 cm(范围0.8 - 9.0 cm)。通过体格检查和磁共振成像(MRI),使用软骨修复组织评分的磁共振观察对患者进行评估。

结果

总共5例患者在术后平均7个月(范围6 - 8个月)成功恢复运动且无限制。在最近一次随访时,这5例患者关节活动范围正常且无关节积液。在平均3年(范围1 - 5年)时,软骨修复组织评分的平均磁共振观察值为85(范围70 - 95)。1例患者在术后1.3年因创伤性损伤治疗失败,随后接受了固定碎片取出和钻孔手术。

结论

在大多数青少年中,使用自体骨栓固定未见骨质部分的软骨碎片成功率令人满意,且MRI扫描证实软骨组织愈合良好。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f327/7787012/31f3db4eb2b8/10.1177_2325967120963050-fig8.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f327/7787012/c7fd9ac2bc6b/10.1177_2325967120963050-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f327/7787012/24cfdd981310/10.1177_2325967120963050-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f327/7787012/3cd65307c2eb/10.1177_2325967120963050-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f327/7787012/844fd80353ca/10.1177_2325967120963050-fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f327/7787012/8b850a485d20/10.1177_2325967120963050-fig5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f327/7787012/fc3c53bcbecc/10.1177_2325967120963050-fig6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f327/7787012/16aee515d38c/10.1177_2325967120963050-fig7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f327/7787012/31f3db4eb2b8/10.1177_2325967120963050-fig8.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f327/7787012/c7fd9ac2bc6b/10.1177_2325967120963050-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f327/7787012/24cfdd981310/10.1177_2325967120963050-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f327/7787012/3cd65307c2eb/10.1177_2325967120963050-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f327/7787012/844fd80353ca/10.1177_2325967120963050-fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f327/7787012/8b850a485d20/10.1177_2325967120963050-fig5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f327/7787012/fc3c53bcbecc/10.1177_2325967120963050-fig6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f327/7787012/16aee515d38c/10.1177_2325967120963050-fig7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f327/7787012/31f3db4eb2b8/10.1177_2325967120963050-fig8.jpg

相似文献

1
Clinical and Radiographic Outcomes After Fixation of Chondral Fragments of the Knee in 6 Adolescents Using Autologous Bone Pegs.6例青少年膝关节软骨碎片采用自体骨栓固定后的临床及影像学结果
Orthop J Sports Med. 2020 Nov 17;8(11):2325967120963050. doi: 10.1177/2325967120963050. eCollection 2020 Nov.
2
A Case Series of Successful Repair of Articular Cartilage Fragments in the Knee.膝关节软骨碎片成功修复的病例系列
Am J Sports Med. 2019 Sep;47(11):2589-2595. doi: 10.1177/0363546519865497.
3
Operative Fixation of Chondral Loose Bodies in Osteochondritis Dissecans in the Knee: A Report of 5 Cases.膝关节剥脱性骨软骨炎软骨游离体的手术固定:5 例报告。
Orthop J Sports Med. 2013 Jul 11;1(2):2325967113496546. doi: 10.1177/2325967113496546. eCollection 2013 Jul.
4
Successful Fixation of Traumatic Articular Cartilage-Only Fragments in the Juvenile and Adolescent Knee: A Case Series.青少年膝关节单纯创伤性关节软骨碎片的成功固定:病例系列
Orthop J Sports Med. 2022 Nov 21;10(11):23259671221138074. doi: 10.1177/23259671221138074. eCollection 2022 Nov.
5
Bone peg fixation of a large chondral fragment in the weight-bearing portion of the lateral femoral condyle in an adolescent: a case report.青少年股骨外侧髁负重部位大软骨碎片的骨栓固定:一例报告
J Med Case Rep. 2014 Sep 23;8:316. doi: 10.1186/1752-1947-8-316.
6
Fixation of Traumatic Chondral-Only Fragments of the Knee in Pediatric and Adolescent Athletes: A Retrospective Multicenter Report.儿童和青少年运动员膝关节单纯创伤性软骨碎片的固定:一项回顾性多中心报告
Orthop J Sports Med. 2018 Feb 7;6(2):2325967117753140. doi: 10.1177/2325967117753140. eCollection 2018 Feb.
7
Surgical Fixation of Chondral-Only Fragments of the Knee: A Case Series With a Mean 4-Year Follow-up.膝关节单纯软骨碎片的手术固定:一项平均随访4年的病例系列研究
Orthop J Sports Med. 2021 Jan 19;9(1):2325967120961391. doi: 10.1177/2325967120961391. eCollection 2021 Jan.
8
Fixation of Acute Chondral Fractures in Adolescent Knees.青少年膝关节急性软骨骨折的固定。
Cartilage. 2021 Dec;13(1_suppl):293S-301S. doi: 10.1177/1947603520941213. Epub 2020 Jul 16.
9
[Osteochondritis dissecans of the femoral condyles: report of 892 cases].[股骨髁剥脱性骨软骨炎:892例报告]
Rev Chir Orthop Reparatrice Appar Mot. 2006 Sep;92(5 Suppl):2S97-2S141.
10
Five-Year Outcomes After Implantation of a Scaffold-Free Tissue-Engineered Construct Generated From Autologous Synovial Mesenchymal Stromal Cells for Repair of Knee Chondral Lesions.使用自体滑膜间充质基质细胞生成的无支架组织工程构建体修复膝关节软骨损伤后的五年结果。
Orthop J Sports Med. 2023 Aug 8;11(8):23259671231189474. doi: 10.1177/23259671231189474. eCollection 2023 Aug.

引用本文的文献

1
Direct Fixation of Acute Chondral-Only Fragments in Young Patients.年轻患者急性单纯软骨碎片的直接固定
Cartilage. 2025 Jul 1:19476035251351781. doi: 10.1177/19476035251351781.
2
Revision Surgery Is the Most Common Definition of Failure in Studies Evaluating Knee Cartilage Restoration Outcomes: A Systematic Review.翻修手术是评估膝关节软骨修复结果的研究中最常见的失败定义:一项系统评价。
Arthrosc Sports Med Rehabil. 2024 Nov 19;7(2):101044. doi: 10.1016/j.asmr.2024.101044. eCollection 2025 Apr.
3
Understanding Osteochondritis Dissecans: A Narrative Review of the Disease Commonly Affecting Children and Adolescents.

本文引用的文献

1
Assessment of Cartilage Growth After Biopsy of Osteochondral Loose Bodies in Adolescent Knees for Use in Autologous Chondrocyte Implantation.青少年膝关节骨软骨游离体活检后用于自体软骨细胞植入的软骨生长评估。
J Pediatr Orthop. 2020 Mar;40(3):110-113. doi: 10.1097/BPO.0000000000001181.
2
Fixation of Traumatic Chondral-Only Fragments of the Knee in Pediatric and Adolescent Athletes: A Retrospective Multicenter Report.儿童和青少年运动员膝关节单纯创伤性软骨碎片的固定:一项回顾性多中心报告
Orthop J Sports Med. 2018 Feb 7;6(2):2325967117753140. doi: 10.1177/2325967117753140. eCollection 2018 Feb.
3
A 20-Year Follow-up After First-Generation Autologous Chondrocyte Implantation.
理解剥脱性骨软骨炎:对常见于儿童和青少年的该疾病的叙述性综述。
Children (Basel). 2024 Apr 22;11(4):498. doi: 10.3390/children11040498.
4
Clinical Outcomes and Return-to-Sport Rates following Fragment Fixation Using Hydroxyapatite/Poly-L-Lactate Acid Threaded Pins for Knee Osteochondritis Dissecans: A Case Series.使用羟基磷灰石/聚左旋乳酸螺纹针治疗膝关节剥脱性骨软骨炎的骨折固定术后临床结果及重返运动率:病例系列
Biomimetics (Basel). 2024 Apr 13;9(4):232. doi: 10.3390/biomimetics9040232.
5
Association of Subchondral Changes With Age and Clinical Outcome in Patients With Osteochondral Fractures in the Knee: MRI Analysis at 1 to 10 Years Postoperatively.膝关节骨软骨骨折患者软骨下改变与年龄及临床结局的相关性:术后1至10年的MRI分析
Orthop J Sports Med. 2022 Jul 25;10(7):23259671221113234. doi: 10.1177/23259671221113234. eCollection 2022 Jul.
6
Osteochondral Peg Fixation for Chondral Fragment of the Knee in Adolescent Patients: A Report of Two Cases.青少年患者膝关节软骨碎片的骨软骨栓固定术:两例报告
Case Rep Orthop. 2021 Jul 8;2021:9958012. doi: 10.1155/2021/9958012. eCollection 2021.
7
Reconstruction of Large Osteochondral Lesions in the Knee: Focus on Fixation Techniques.膝关节大的骨软骨损伤的重建:聚焦于固定技术。
Life (Basel). 2021 Jun 10;11(6):543. doi: 10.3390/life11060543.
第一代自体软骨细胞植入术后20年随访
Am J Sports Med. 2017 Oct;45(12):2751-2761. doi: 10.1177/0363546517716631. Epub 2017 Jul 26.
4
Open Reduction Internal Fixation of Isolated Chondral Fragments Without Osseous Attachment in the Knee: A Case Series.膝关节无骨附着的孤立软骨碎片切开复位内固定:病例系列
Orthop J Sports Med. 2017 Mar 17;5(3):2325967117696281. doi: 10.1177/2325967117696281. eCollection 2017 Mar.
5
High Rate of Osteoarthritis After Osteochondritis Dissecans Fragment Excision Compared With Surgical Restoration at a Mean 16-Year Follow-up.平均16年随访结果显示,与手术修复相比,剥脱性骨软骨炎碎片切除术后骨关节炎发生率较高。
Am J Sports Med. 2017 Jul;45(8):1799-1805. doi: 10.1177/0363546517699846. Epub 2017 Apr 18.
6
Intralesional Osteophyte Regrowth Following Autologous Chondrocyte Implantation after Previous Treatment with Marrow Stimulation Technique.先前采用骨髓刺激技术治疗后自体软骨细胞植入术后的病灶内骨赘再生
Cartilage. 2017 Apr;8(2):131-138. doi: 10.1177/1947603516653208. Epub 2016 Jul 7.
7
Long-term Outcomes of Autologous Chondrocyte Implantation in Adolescent Patients.青少年患者自体软骨细胞移植的长期疗效
Am J Sports Med. 2017 Apr;45(5):1066-1074. doi: 10.1177/0363546516682492. Epub 2017 Jan 27.
8
Long-Term Outcomes after Autologous Chondrocyte Implantation: A Systematic Review at Mean Follow-Up of 11.4 Years.自体软骨细胞植入后的长期疗效:平均随访11.4年的系统评价
Cartilage. 2016 Oct;7(4):298-308. doi: 10.1177/1947603516630786. Epub 2016 Mar 3.
9
Long-term Outcomes After Osteochondral Autograft Transfer: A Systematic Review at Mean Follow-up of 10.2 Years.自体骨软骨移植后的长期疗效:平均随访10.2年的系统评价
Arthroscopy. 2016 Jun;32(6):1174-84. doi: 10.1016/j.arthro.2015.11.037. Epub 2016 Feb 19.
10
Bone peg fixation of a large chondral fragment in the weight-bearing portion of the lateral femoral condyle in an adolescent: a case report.青少年股骨外侧髁负重部位大软骨碎片的骨栓固定:一例报告
J Med Case Rep. 2014 Sep 23;8:316. doi: 10.1186/1752-1947-8-316.