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吲哚菁绿荧光引导下脐尿管癌根治性膀胱部分切除术及盆腔淋巴结清扫术

Indocyanine Green Fluorescence-Guided Partial Cystectomy and Pelvic Lymphadenectomy for Urachal Carcinoma.

作者信息

Ito Katsuhiro, Takahashi Toshifumi, Kanno Toru, Okada Takashi, Higashi Yoshihito, Yamada Hitoshi

机构信息

Department of Urology, Ijinkai Takeda General Hospital, Kyoto, Japan.

出版信息

J Endourol Case Rep. 2020 Dec 29;6(4):275-277. doi: 10.1089/cren.2020.0025. eCollection 2020.

DOI:10.1089/cren.2020.0025
PMID:33457653
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7803199/
Abstract

Intraoperative indocyanine green near-infrared fluorescence guidance is an emerging optical imaging technology to facilitate better understanding of surgical landmarks. Herein, this technique was applied during the surgery for urachal carcinoma. A 50-year-old man with urachal carcinoma underwent laparoscopic partial cystectomy and pelvic lymph node dissection (PLND). Before the laparoscopic surgery, indocyanine green was injected cystoscopically around the tumor at the submucosa level. The tumor location and lymph drainage were clearly viewed. The lymphatic flow was along the superior vesical artery and the umbilical ligament. The obturator and external lymph nodes were not fluoresced. Template PLND was performed. Partial cystectomy was completed with cystoscopic monitoring of the margin and with endoscopic stapler to avoid tumor spillage. Intraoperative indocyanine green fluorescence views lymph drainage and tumor location and is useful to improve the quality of PLND and partial cystectomy.

摘要

术中吲哚菁绿近红外荧光引导是一种新兴的光学成像技术,有助于更好地识别手术标志。在此,该技术应用于脐尿管癌手术。一名50岁脐尿管癌男性患者接受了腹腔镜部分膀胱切除术和盆腔淋巴结清扫术(PLND)。在腹腔镜手术前,通过膀胱镜在肿瘤黏膜下层周围注射吲哚菁绿。肿瘤位置和淋巴引流清晰可见。淋巴液沿膀胱上动脉和脐韧带流动。闭孔淋巴结和腹股沟淋巴结未显荧光。进行了标准的PLND。在膀胱镜监测切缘的情况下,使用内镜吻合器完成部分膀胱切除术,以避免肿瘤播散。术中吲哚菁绿荧光可观察淋巴引流和肿瘤位置,有助于提高PLND和部分膀胱切除术的质量。

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本文引用的文献

1
Indocyanine Green (ICG) in Urologic Surgery.吲哚菁绿(ICG)在泌尿科手术中的应用。
Urology. 2019 Oct;132:10-17. doi: 10.1016/j.urology.2019.05.008. Epub 2019 May 23.
2
Anatomical localization and clinical impact of sentinel lymph nodes based on patterns of pelvic lymphatic drainage in clinically localized prostate cancer.基于临床局限性前列腺癌盆腔淋巴引流模式的前哨淋巴结的解剖定位及临床影响
Prostate. 2018 May;78(6):419-425. doi: 10.1002/pros.23486. Epub 2018 Jan 25.
3
Molecular Targeted Fluorescence-Guided Intraoperative Imaging of Bladder Cancer Nodal Drainage Using Indocyanine Green During Radical and Partial Cystectomy.在根治性膀胱切除术和部分膀胱切除术中使用吲哚菁绿对膀胱癌淋巴结引流进行分子靶向荧光引导的术中成像。
Curr Urol Rep. 2016 Oct;17(10):74. doi: 10.1007/s11934-016-0633-z.
4
Clinical, prognostic, and therapeutic aspects of urachal carcinoma-A comprehensive review with meta-analysis of 1,010 cases.脐尿管癌的临床、预后及治疗方面——1010例病例的综合综述与荟萃分析
Urol Oncol. 2016 Sep;34(9):388-98. doi: 10.1016/j.urolonc.2016.04.012. Epub 2016 Jun 3.