Keesman Rick, van der Bijl Erik, Janssen Tomas M, Vijlbrief Tineke, Pos Floris J, van der Heide Uulke A
Department of Radiation Oncology, Netherlands Cancer Institute, Plesmanlaan 121, 1066CX Amsterdam, The Netherlands.
Phys Imaging Radiat Oncol. 2020 Aug 12;15:85-90. doi: 10.1016/j.phro.2020.07.010. eCollection 2020 Jul.
BACKGROUND & PURPOSE: Metallic prostheses distort the magnetic field during magnetic resonance imaging (MRI), leading to geometric distortions and signal loss. The purpose of this work was to develop a method to determine eligibility for MRI-guided radiotherapy (MRIgRT) on a per patient basis by estimating the magnitude of geometric distortions inside the clinical target volume (CTV).
MATERIALS & METHODS: Three patients with prostate cancer and hip prosthesis, treated using MRIgRT, were included. Eligibility for MRIgRT was based on computed tomography and associated CTV delineations, together with a field-distortion (B0) map and anatomical images acquired during MR simulation. To verify the method, B0 maps made during MR simulation and each MRIgRT treatment fraction were compared.
Estimates made during MR simulation of the magnitude of distortions inside the CTV were 0.43 mm, 0.19 mm and 2.79 mm compared to the average over all treatment fractions of 1.40 mm, 0.32 mm and 1.81 mm, per patient respectively.
B0 map acquisitions prior to treatment can be used to estimate the magnitude of distortions during MRIgRT to guide the decision on eligibility for MRIgRT of prostate cancer patients with metallic hip implants.
金属假体在磁共振成像(MRI)过程中会使磁场发生畸变,导致几何畸变和信号丢失。本研究的目的是开发一种方法,通过估计临床靶区(CTV)内几何畸变的大小,逐例确定患者是否适合进行MRI引导的放射治疗(MRIgRT)。
纳入3例使用MRIgRT治疗的前列腺癌合并髋关节假体患者。MRIgRT的适用性基于计算机断层扫描及相关CTV轮廓,以及在磁共振模拟期间获取的场畸变(B0)图和解剖图像。为验证该方法,比较了磁共振模拟期间及每次MRIgRT治疗分次所制作的B0图。
每位患者在磁共振模拟期间对CTV内畸变大小的估计分别为0.43毫米、0.19毫米和2.79毫米,而所有治疗分次的平均值分别为1.40毫米、0.32毫米和1.81毫米。
治疗前采集B0图可用于估计MRIgRT期间的畸变大小,以指导对有金属髋关节植入物的前列腺癌患者是否适合进行MRIgRT的决策。