Franco Paloma, Bellesi Yanina, Nocent Eliana, Strappa Agostina, Galeano María L
Hospital General de Niños Pedro de Elizalde (HGNPE), Ciudad Autónoma de Buenos Aires, Argentina.
Arch Argent Pediatr. 2021 Feb;119(1):e58-e60. doi: 10.5546/aap.2021.e58.
The SARS-CoV-2 virus, responsible for the COVID-19 pandemic, is an emerging infectious agent. The knowledge of both its infectivity mechanisms and the possible complications and specific treatments is the subject of constant research. To understand the involvement of the central nervous system in children, the behavior of this germ is studied based on the neuroinvasive properties of certain respiratory viruses, the neurological damage caused by other coronaviruses, and the clinical manifestations in adults with COVID-19. We describe the clinical case of a 2-month-old patient who consulted for fever without a focus with detection of SARSCoV- 2 by reverse transcription polymerase chain reaction in nasopharyngeal secretions and cerebrospinal fluid. The infant presented good evolution, with resolution of the fever and without compromise or neurological manifestations.
导致新冠疫情的严重急性呼吸综合征冠状病毒2（SARS-CoV-2）是一种新出现的感染源。对其感染机制、可能的并发症及特效治疗方法的了解是持续研究的课题。为了解中枢神经系统在儿童中的受累情况，基于某些呼吸道病毒的神经侵袭特性、其他冠状病毒所致的神经损伤以及新冠成人患者的临床表现，对这种病原体的行为进行了研究。我们描述了一名2个月大患者的临床病例，该患者因无明确病因的发热前来就诊，通过逆转录聚合酶链反应在鼻咽分泌物和脑脊液中检测出SARS-CoV-2。婴儿病情进展良好，发热消退，未出现功能障碍或神经学表现。
