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日常生活活动和工作记忆在儿科注意缺陷多动障碍(ADHD)中的作用。

Activities of daily living and working memory in pediatric attention-deficit/hyperactivity disorder (ADHD).

机构信息

Department of Psychology, Florida State University, Tallahassee, FL, USA.

出版信息

Child Neuropsychol. 2021 May;27(4):468-490. doi: 10.1080/09297049.2020.1866521. Epub 2021 Jan 18.

Abstract

Most children with ADHD have impaired working memory abilities. These working memory deficits predict impairments in activities of daily living (ADLs) for adults with ADHD. However, our understanding of the relation between pediatric ADHD and ADLs is limited. Thus, this study aimed to examine (1) the extent to which pediatric ADHD is associated with ADL difficulties; and if so (2) the extent to which these difficulties are related to their well-documented working memory difficulties and/or core ADHD inattentive and hyperactive/impulsive symptom domains. A well-characterized, clinically evaluated sample of 141 children ages 8-13 years ( = 10.36, = 1.46; 51 girls; 70% White/non-Hispanic) were administered a battery of well-validated working memory tests and assessed for ADHD symptoms (teacher-ratings) and ADL difficulties (parent-ratings); cross-informant reports were used to control for mono-informant bias. Children with ADHD exhibited medium magnitude difficulties with ADLs ( = 0.61, p < .005, 38% impaired). Results of the bias-corrected, bootstrapped conditional effects model indicated that lower working memory predicted reduced performance of age-expected ADLs (=0.28) and greater ADHD inattentive (= -0.40) and hyperactive/impulsive symptoms (= -0.16). Greater inattentive, but not hyperactive/impulsive, symptoms predicted greater ADL difficulties (= -0.36) even after controlling for working memory. Interestingly, working memory exerted a significant indirect effect on ADLs via inattentive (indirect effect: = 0.15, effect ratio = .54) but not hyperactive/impulsive symptoms. These findings implicate ADHD inattentive symptoms as a potential mechanism underlying ADL difficulties for children with ADHD, both independently and via working memory's role in regulating attention.

摘要

大多数患有注意力缺陷多动障碍(ADHD)的儿童的工作记忆能力受损。这些工作记忆缺陷预测了患有 ADHD 的成年人在日常生活活动(ADL)中的障碍。然而,我们对儿科 ADHD 与 ADL 之间关系的理解是有限的。因此,本研究旨在检查:(1)儿科 ADHD 与 ADL 困难的关联程度;如果是这样,(2)这些困难与他们众所周知的工作记忆困难以及/或者 ADHD 注意力不集中和多动/冲动症状领域的核心症状的关联程度。一个经过良好特征描述和临床评估的 141 名 8-13 岁儿童样本(= 10.36,= 1.46;51 名女孩;70%为白种人/非西班牙裔)接受了一系列经过充分验证的工作记忆测试,并接受了 ADHD 症状(教师评定)和 ADL 困难(家长评定)的评估;交叉报告用于控制单报告偏差。患有 ADHD 的儿童在 ADL 方面表现出中等程度的困难(= 0.61,p <.005,38%的人受损)。经过偏差校正、自举条件效应模型的结果表明,较低的工作记忆预测了年龄预期的 ADL 表现下降(= 0.28),以及注意力不集中(= -0.40)和多动/冲动症状(= -0.16)增加。更大的注意力不集中症状,但不是多动/冲动症状,即使在控制工作记忆的情况下,也能预测更大的 ADL 困难(= -0.36)。有趣的是,工作记忆通过注意力不集中对 ADL 产生了显著的间接影响(间接效应:= 0.15,效应比=.54),而不是多动/冲动症状。这些发现表明,ADHD 注意力不集中症状是 ADHD 儿童 ADL 困难的一个潜在机制,既独立于工作记忆在调节注意力方面的作用,也通过工作记忆的作用。

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