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2
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Kidney Int Rep. 2018 Jun 2;3(5):1135-1143. doi: 10.1016/j.ekir.2018.05.011. eCollection 2018 Sep.
3
Prevalence of CKD, Diabetes, and Hypertension in Rural Tanzania.坦桑尼亚农村地区慢性肾脏病、糖尿病和高血压的患病率
Kidney Int Rep. 2018 Apr 22;3(4):905-915. doi: 10.1016/j.ekir.2018.04.006. eCollection 2018 Jul.
4
Prevalence and risk factors associated with chronic kidney disease in adults living in 3 different altitude regions in the Tibetan Plateau.居住在青藏高原 3 个不同海拔地区的成年人中慢性肾脏病的患病率及相关危险因素。
Clin Chim Acta. 2018 Jun;481:212-217. doi: 10.1016/j.cca.2018.03.025. Epub 2018 Mar 21.
5
Global challenges in kidney diseases.肾脏疾病的全球挑战。
Nephrol Dial Transplant. 2018 Mar 1;33(3):371-372. doi: 10.1093/ndt/gfy037.
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2017 Guidelines for Arterial Hypertension Management in Primary Health Care in Portuguese Language Countries.2017年葡萄牙语国家初级卫生保健中动脉高血压管理指南。
Arq Bras Cardiol. 2017 Nov;109(5):389-396. doi: 10.5935/abc.20170165.
7
Brazilian Chronic Dialysis Survey 2016.2016年巴西慢性透析调查
J Bras Nefrol. 2017 Jul-Sep;39(3):261-266. doi: 10.5935/0101-2800.20170049.
8
Global kidney health 2017 and beyond: a roadmap for closing gaps in care, research, and policy.全球肾脏健康 2017 及以后:缩小照护、研究和政策差距的路线图。
Lancet. 2017 Oct 21;390(10105):1888-1917. doi: 10.1016/S0140-6736(17)30788-2. Epub 2017 Apr 20.
9
Chronic Kidney Disease.慢性肾脏病。
Lancet. 2017 Mar 25;389(10075):1238-1252. doi: 10.1016/S0140-6736(16)32064-5. Epub 2016 Nov 23.
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Chronic kidney disease and cardiovascular risk in six regions of the world (ISN-KDDC): a cross-sectional study.世界六个地区的慢性肾脏病和心血管风险(ISN-KDDC):一项横断面研究。
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慢性肾脏病在伴有动脉高血压和/或糖尿病的巴西人群中的流行情况。

Prevalence of chronic kidney disease in Brazilians with arterial hypertension and/or diabetes mellitus.

机构信息

Department of Nutrition and Health, Federal University of Viçosa, Graduate Program in Nutrition and Health, Viçosa, MG, Brazil.

Nutrition Course, School of Medicine, Federal University of Uberlândia, Uberlândia, MG, Brazil.

出版信息

J Clin Hypertens (Greenwich). 2020 Sep;22(9):1666-1673. doi: 10.1111/jch.13980. Epub 2020 Aug 9.

DOI:10.1111/jch.13980
PMID:33460313
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8029734/
Abstract

The present study aimed to evaluate the prevalence of chronic kidney disease (CKD) in individuals with arterial hypertension (AH) and/or diabetes mellitus (DM) accompanied by Primary Health Care (PHC) in Brazil. The estimated glomerular filtration rate (eGFR) based on creatinine, and urinary albumin-to-creatinine ratio (ACR) were measured in 841 subjects with AH and/or DM, followed by PHC in the city of Viçosa. The CKD was diagnosed according to KDIGO criteria. Sociodemographic, clinical, and anthropometric factors related to the prevalence of CKD were investigated through multiple logistic regression. The prevalence of hidden CKD was 15.4%. Of these, 7.5% were identified by albuminuria (ACR ≥30 mg/g) with slightly decreased eGFR. Age, baseline disease, waist circumference (WC), and systolic blood pressure remained associated with CKD after multivariate analysis. The two major risk factors for hidden CKD were the presence of AH in association with DM and an increase in age. Hidden CKD was more common within people with AH and DM, and with high WC, glycosylated hemoglobin, and serum phosphorus as well as male gender and decreased serum albumin. This knowledge of risk associations can help avoid progression to CKD.

摘要

本研究旨在评估巴西伴有初级卫生保健(PHC)的动脉高血压(AH)和/或糖尿病(DM)患者中慢性肾脏病(CKD)的患病率。在维索萨市,对 841 名患有 AH 和/或 DM 的患者进行了基于肌酐的估计肾小球滤过率(eGFR)和尿白蛋白与肌酐比值(ACR)的测量,并进行了 PHC。根据 KDIGO 标准诊断 CKD。通过多因素逻辑回归调查了与 CKD 患病率相关的社会人口学、临床和人体测量学因素。隐匿性 CKD 的患病率为 15.4%。其中,7.5% 通过白蛋白尿(ACR≥30mg/g)和轻度降低的 eGFR 确定。在多变量分析后,年龄、基线疾病、腰围(WC)和收缩压与 CKD 仍然相关。隐匿性 CKD 的两个主要危险因素是 AH 与 DM 并存以及年龄增长。AH 和 DM 患者、WC 高、糖化血红蛋白和血清磷高以及男性和血清白蛋白降低的患者中,隐匿性 CKD 更为常见。了解这些风险关联有助于避免 CKD 的进展。