Federal University of Ceará, 1608 Prof. Costa Mendes Street, Didactics Building, 5th floor, Rodolfo Teófilo, Fortaleza 60430-160, Brazil.
Laboratório de Saúde Pública do Estado do Ceará (LACEN), 2405 Barão de Studart Avenue, Dionísio Torres, Fortaleza 60120-002, Brazil.
Trans R Soc Trop Med Hyg. 2021 Sep 3;115(9):1070-1079. doi: 10.1093/trstmh/traa182.
Outbreaks of Chikungunya virus (CHIKV) occurred in Brazil during 2015-2017. Fortaleza was the city that reported the most cases.
The first round of a cohort study was conducted among women aged 15-39 y in Fortaleza, Brazil, in 2018 (Zika in Fortaleza). We collected sera to detect CHIKV IgG and IgM antibodies. Factors for CHIKV infection were identified using a Poisson regression model.
We evaluated 1466 serum samples and 13.8% and 37.2% of women were found positive for CHIKV IgM and IgG antibodies, respectively. Living with more than four others in the same house and having an abandoned house nearby were associated with CHIKV infection. Being currently pregnant was associated with a decreased probability of CHIKV infection, which was also associated with pregnant women reporting using more repellent, both inside and outside the house, than non-pregnant women.
Crowding in households and abandoned houses nearby can increase potential transmission. Policies providing better living conditions and regulation of abandoned sites and buildings are necessary to control the mosquito population. Programmes providing repellant at low or no cost to pregnant women should be implemented in the neighbourhoods where arbovirus infections are endemic.
2015 年至 2017 年，巴西暴发了基孔肯雅热病毒（CHIKV）疫情。福塔莱萨是报告病例最多的城市。
2018 年，巴西福塔莱萨市对年龄在 15-39 岁的女性进行了第一轮队列研究（福塔莱萨的寨卡病毒）。我们收集血清以检测 CHIKV IgG 和 IgM 抗体。使用泊松回归模型确定 CHIKV 感染的因素。
我们评估了 1466 份血清样本，分别有 13.8%和 37.2%的女性 CHIKV IgM 和 IgG 抗体检测呈阳性。与四人以上同住一屋以及附近有废弃房屋与 CHIKV 感染有关。目前怀孕与 CHIKV 感染的可能性降低有关，与未怀孕的女性相比，孕妇报告在屋内和屋外使用更多驱虫剂也与 CHIKV 感染有关。
家庭拥挤和附近废弃房屋可能会增加潜在的传播风险。需要提供更好的生活条件，并对废弃场所和建筑物进行监管，以控制蚊虫数量。应在地方性虫媒病毒感染地区向孕妇提供低成本甚至免费的驱虫剂方案。
