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通过计算机断层扫描对股动脉深度进行标准化测量以预测经导管主动脉瓣植入术后的血管并发症。

Standardized Measurement of Femoral Artery Depth by Computed Tomography to Predict Vascular Complications After Transcatheter Aortic Valve Implantation.

机构信息

Normandie Univ, UNIROUEN, Inserm U1096, CHU Rouen, Department of Cardiology, FHU CARNAVAL, F-76000 Rouen, France.

Normandie Univ, UNIROUEN, Inserm U1096, CHU Rouen, Department of Cardiology, FHU CARNAVAL, F-76000 Rouen, France.

出版信息

Am J Cardiol. 2021 Apr 15;145:119-127. doi: 10.1016/j.amjcard.2020.12.089. Epub 2021 Jan 15.

DOI:10.1016/j.amjcard.2020.12.089
PMID:33460601
Abstract

Vascular complications (VCs) are difficult to predict and remain an important issue after transfemoral (TF) transcatheter aortic valve implantation (TAVI) although their incidence has decreased with size reduction of introducers. We aimed to evaluate a standardized measurement of femoral artery depth (FAD) using computed tomography (CT) to predict VCs after TAVI. We performed a retrospective study of 679 TF TAVI patients. We evaluated a standardized CT method to measure FAD immediately above the bifurcation. Sheath-to-femoral-artery ratio (SFAR), calcification, and tortuosity were also evaluated. VCs were defined by the Valve Academic Research Consortium (VARC)-2. Receiver operating characteristic (ROC) curves were used to predict major VCs and the need for a stent-graft. The median values of FAD and SFAR were 49.0 (36.2 to 66.7) mm and 0.95 (0.81 to 1.18), respectively. Major VCs occurred in 37 (5.4%) patients and a stent-graft was required in 49 (7.1%) patients. FAD predicted the need for a stent-graft [0.61 (0.51 to 0.70), p = 0.04] but not major VCs [0.52 (0.40 to 0.63), p = 0.76]. In contrast, SFAR did not predict the need for a stent-graft [0.53 (0.43 to 0.62), p = 0.61] but predicted major VCs [0.70 (0.58 to 0.81), p = 0.001]. Calcification and tortuosity predicted neither major VCs nor the need for a stent-graft. In conclusion, the results of our study suggest that CT measurements of FAD and SFAR provide additional information to predict major VCs and the need for a femoral stent-graft after TF TAVI.

摘要

血管并发症(VCs)很难预测,尽管随着引入器尺寸的减小,其发生率已经降低,但在经股(TF)经导管主动脉瓣植入(TAVI)后仍然是一个重要问题。我们旨在评估使用计算机断层扫描(CT)测量股动脉深度(FAD)的标准化方法,以预测 TAVI 后的 VCs。我们对 679 例 TF TAVI 患者进行了回顾性研究。我们评估了一种标准化 CT 方法,以测量分叉上方的 FAD。还评估了鞘管至股动脉比(SFAR)、钙化和迂曲程度。VCs 由 Valve Academic Research Consortium(VARC)-2 定义。使用受试者工作特征(ROC)曲线预测主要 VCs 和需要支架移植的情况。FAD 和 SFAR 的中位数分别为 49.0(36.2 至 66.7)mm 和 0.95(0.81 至 1.18)。37 例(5.4%)患者发生主要 VCs,49 例(7.1%)患者需要支架移植。FAD 预测需要支架移植[0.61(0.51 至 0.70),p=0.04],但不能预测主要 VCs[0.52(0.40 至 0.63),p=0.76]。相比之下,SFAR 既不能预测支架移植的需要[0.53(0.43 至 0.62),p=0.61],也不能预测主要 VCs[0.70(0.58 至 0.81),p=0.001]。钙化和迂曲程度既不能预测主要 VCs,也不能预测支架移植的需要。总之,我们的研究结果表明,CT 测量 FAD 和 SFAR 可提供额外信息,以预测 TF TAVI 后主要 VCs 和股动脉支架移植的需要。

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