Non-Communicable Diseases Research Center, Alborz University of Medical Sciences, Karaj, Iran.
Department of Pediatrics, Imam Ali Hospital, Alborz University of Medical Sciences, Karaj, Iran.
Iran J Allergy Asthma Immunol. 2020 Dec 19;19(6):660-666. doi: 10.18502/ijaai.v19i6.4935.
Asthma is the most common chronic inflammatory respiratory disorder in children. This study was designed to assess the prevalence of asthma in 13-14-year-old adolescents in Karaj, Alborz province in Iran, using the international study of asthma and allergies in childhood (ISAAC) questionnaire. Totally 950 adolescents attending 40 schools located in 4 regions of Karaj city were enrolled in the survey. The Persian version of the ISAAC questionnaire was filled by 13-14-year-old students. Multi-stage clustered random sampling was used to divide the city of Karaj into four educational districts. Ever wheezing was reported in 22% of the individuals; 10.52% claimed to have wheeze in the last 12 months and 22.73% had during or after exercise. The experience of wheezing in the last 12 months was more prevalent among males (11.73% vs. 9.38%; p<0.05). However, having a history of asthma was higher among males (7.55% vs. 3.47%; p<0.05). History of hospitalization (60.8%), family history of asthma (49.4%), and history of food allergy (42.3%) were found to be the most frequent characteristics significantly associated with" ever wheezing" (p<0.05). The prevalence of wheezing in the last 12 months, as a major index of current asthma, was 10% which was close to the national average. However, nocturnal cough and exercise-induced wheezing were higher in Karaj compared to other cities of Iran; which could be related to the high level of air pollution in this industrial area.
哮喘是儿童最常见的慢性炎症性呼吸道疾病。本研究旨在使用国际儿童哮喘和过敏研究(ISAAC)问卷评估伊朗阿尔博兹省卡拉季市 13-14 岁青少年哮喘的患病率。共有 950 名青少年参加了位于卡拉季市 4 个地区的 40 所学校的调查。13-14 岁的学生填写了 ISAAC 问卷的波斯语版本。采用多阶段聚类随机抽样法将卡拉季市分为四个教育区。共有 22%的个体报告有过喘息;10.52%称过去 12 个月有喘息,22.73%在运动期间或之后有喘息。过去 12 个月有喘息的经历在男性中更为常见(11.73%比 9.38%;p<0.05)。然而,男性中哮喘病史更高(7.55%比 3.47%;p<0.05)。住院史(60.8%)、哮喘家族史(49.4%)和食物过敏史(42.3%)是与“过去有过喘息”显著相关的最常见特征(p<0.05)。过去 12 个月喘息的患病率作为当前哮喘的主要指标为 10%,接近全国平均水平。然而,夜间咳嗽和运动诱发的喘息在卡拉季比伊朗其他城市更为常见;这可能与这个工业区的空气污染水平较高有关。