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白藜芦醇的抗炎作用及机制。

Anti-Inflammatory Action and Mechanisms of Resveratrol.

机构信息

College of Animal Science and Technology, Hunan Agricultural University, Changsha 410128, China.

Huaihua Institute of Agricultural Sciences, No.140 Yingfeng East Road, Hecheng District, Huaihua 418000, China.

出版信息

Molecules. 2021 Jan 5;26(1):229. doi: 10.3390/molecules26010229.

DOI:10.3390/molecules26010229
PMID:33466247
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7796143/
Abstract

Resveratrol (3,4',5-trihy- droxystilbene), a natural phytoalexin polyphenol, exhibits anti-oxidant, anti-inflammatory, and anti-carcinogenic properties. This phytoalexin is well-absorbed and rapidly and extensively metabolized in the body. Inflammation is an adaptive response, which could be triggered by various danger signals, such as invasion by microorganisms or tissue injury. In this review, the anti-inflammatory activity and the mechanism of resveratrol modulates the inflammatory response are examined. Multiple experimental studies that illustrate regulatory mechanisms and the immunomodulatory function of resveratrol both in vivo and in vitro. The data acquired from those studies are discussed.

摘要

白藜芦醇(3,4',5-三羟基二苯乙烯),一种天然植物抗毒素多酚,具有抗氧化、抗炎和抗癌特性。这种植物抗毒素在体内具有良好的吸收性,并能迅速广泛地代谢。炎症是一种适应性反应,可由各种危险信号触发,如微生物入侵或组织损伤。在这篇综述中,研究了白藜芦醇的抗炎活性和调节炎症反应的机制。多项实验研究说明了白藜芦醇在体内和体外的调节机制和免疫调节功能。讨论了从这些研究中获得的数据。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4c8d/7796143/d3d0e3fbe1ea/molecules-26-00229-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4c8d/7796143/920d666ed13c/molecules-26-00229-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4c8d/7796143/cb9da540805c/molecules-26-00229-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4c8d/7796143/d3d0e3fbe1ea/molecules-26-00229-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4c8d/7796143/920d666ed13c/molecules-26-00229-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4c8d/7796143/cb9da540805c/molecules-26-00229-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4c8d/7796143/d3d0e3fbe1ea/molecules-26-00229-g003.jpg

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