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一项针对帕金森病老年患者的创新型个性化管理方案:新概念与未来方向。

An Innovative Personalised Management Program for Older Adults with Parkinson's Disease: New Concepts and Future Directions.

作者信息

Varma Piyush, Narayan Lakshanaa, Alty Jane, Painter Virginia, Padmakumar Chandrasekhara

机构信息

Faculty of Medicine, Imperial College London, London SW7 2BU, UK.

Joint Medical Program, University of Newcastle, Callaghan, NSW 2308, Australia.

出版信息

J Pers Med. 2021 Jan 14;11(1):43. doi: 10.3390/jpm11010043.

DOI:10.3390/jpm11010043
PMID:33466580
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7828689/
Abstract

Parkinson's disease is a heterogeneous clinical syndrome. Parkinson's disease in older persons presents with a diverse array of clinical manifestations leading to unique care needs. This raises the need for the healthcare community to proactively address the care needs of older persons with Parkinson's disease. Though it is tempting to categorise different phenotypes of Parkinson's disease, a strong evidence based for the same is lacking. There is considerable literature describing the varying clinical manifestations in old age. This article aims to review the literature looking for strategies in personalising the management of an older person with Parkinson's disease.

摘要

帕金森病是一种异质性临床综合征。老年帕金森病患者表现出多种多样的临床表现,从而产生独特的护理需求。这就使得医疗保健界有必要积极应对老年帕金森病患者的护理需求。尽管对帕金森病的不同表型进行分类很诱人,但缺乏基于此的有力证据。有大量文献描述了老年患者的不同临床表现。本文旨在回顾相关文献,寻找针对老年帕金森病患者进行个性化管理的策略。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b7a2/7828689/e1acbade12da/jpm-11-00043-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b7a2/7828689/01e3ae503081/jpm-11-00043-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b7a2/7828689/e1acbade12da/jpm-11-00043-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b7a2/7828689/01e3ae503081/jpm-11-00043-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b7a2/7828689/e1acbade12da/jpm-11-00043-g002.jpg

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本文引用的文献

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Integrated and patient-centred management of Parkinson's disease: a network model for reshaping chronic neurological care.帕金森病的综合与以患者为中心的管理:重塑慢性神经疾病护理的网络模型
Lancet Neurol. 2020 Jul;19(7):623-634. doi: 10.1016/S1474-4422(20)30064-8. Epub 2020 May 25.
2
A roadmap for implementation of patient-centered digital outcome measures in Parkinson's disease obtained using mobile health technologies.利用移动健康技术实施以患者为中心的帕金森病数字结局测量的路线图。
Mov Disord. 2019 May;34(5):657-663. doi: 10.1002/mds.27671. Epub 2019 Mar 22.
3
Parkinson's Disease in the Era of Personalised Medicine: One Size Does Not Fit All.
个性化医疗时代的帕金森病:一刀切并不适用于所有人。
Drugs Aging. 2019 Feb;36(2):103-113. doi: 10.1007/s40266-018-0624-5.
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Parkinson's Disease Subtypes Identified from Cluster Analysis of Motor and Non-motor Symptoms.从运动和非运动症状聚类分析中识别出的帕金森病亚型
Front Aging Neurosci. 2017 Sep 20;9:301. doi: 10.3389/fnagi.2017.00301. eCollection 2017.
5
Personalized Medicine and Nonmotor Symptoms in Parkinson's Disease.帕金森病的个性化医疗与非运动症状
Int Rev Neurobiol. 2017;134:1257-1281. doi: 10.1016/bs.irn.2017.05.015.
6
Treatment of Older Parkinson's Disease.老年帕金森病的治疗
Int Rev Neurobiol. 2017;132:381-405. doi: 10.1016/bs.irn.2017.01.005. Epub 2017 Feb 15.
7
Parkinson's: a syndrome rather than a disease?帕金森病:一种综合征而非一种疾病?
J Neural Transm (Vienna). 2017 Aug;124(8):907-914. doi: 10.1007/s00702-016-1667-6. Epub 2016 Dec 27.
8
Parkinson's disease in the older patient.老年患者的帕金森病
Clin Med (Lond). 2016 Aug;16(4):376-8. doi: 10.7861/clinmedicine.16-4-376.
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Nonmotor features of Parkinson's disease subtypes.帕金森病亚型的非运动特征。
Mov Disord. 2016 Aug;31(8):1095-102. doi: 10.1002/mds.26510. Epub 2016 Feb 10.
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Patients' anxiety and hope: predictors and adherence intentions in an acute care context.患者的焦虑与希望:急性护理环境中的预测因素及依从意愿
Health Expect. 2015 Dec;18(6):3034-43. doi: 10.1111/hex.12288. Epub 2014 Oct 18.