Institut Technologique FCBA, Allée de Boutaut, BP 227, F-33028 Bordeaux, France.
Laboratoire Phenobio SAS, ZA Les Pins Verts, 22 Allée de Migelane, F-33650 Saucats, France.
Molecules. 2021 Jan 14;26(2):405. doi: 10.3390/molecules26020405.
is a fungal pathogen that can colonize small-grain cereals and maize and secrete type B trichothecene (TCTB) mycotoxins. The development of environmental-friendly strategies guaranteeing the safety of food and feed is a key challenge facing agriculture today. One of these strategies lies on the promising capacity of products issued from natural sources to counteract crop pests. In this work, the in vitro efficiency of sixteen extracts obtained from eight natural sources using subcritical water extraction at two temperatures was assessed against fungal growth and TCTB production by . Maritime pine sawdust extract was shown to be extremely efficient, leading to a significant inhibition of up to 89% of the fungal growth and up to 65% reduction of the mycotoxin production by . Liquid chromatography/mass spectrometry analysis of this active extract revealed the presence of three families of phenolics with a predominance of methylated compounds and suggested that the abundance of methylated structures, and therefore of hydrophobic compounds, could be a primary factor underpinning the activity of the maritime pine sawdust extract. Altogether, our data support that wood/forest by-products could be promising sources of bioactive compounds for controlling and its production of mycotoxins.
是一种真菌病原体，能够定殖于小粒谷类作物和玉米，并分泌 B 型单端孢霉烯族毒素（TCTB）真菌毒素。开发能够保证食品安全和饲料安全的环保型策略是当今农业面临的关键挑战之一。这些策略之一在于利用天然产物的有希望的能力来对抗作物害虫。在这项工作中，评估了使用亚临界水提取在两种温度下从八种天然来源获得的十六种提取物对 的真菌生长和 TCTB 产生的体外效率。结果表明，马尾松木屑提取物具有极高的效率，导致真菌生长的抑制率高达 89%，真菌毒素产量的降低率高达 65%。对这种活性提取物的液相色谱/质谱分析表明，存在三类酚类化合物，其中以甲基化化合物为主，这表明甲基化结构的丰度，也就是疏水性化合物的丰度，可能是马尾松木屑提取物活性的主要因素。总的来说，我们的数据支持木材/森林副产品可能是控制 和其产生真菌毒素的生物活性化合物的有前途的来源。
