Ferreira-Santos Pedro, Genisheva Zlatina, Botelho Cláudia, Santos Joana, Ramos Carla, Teixeira José A, Rocha Cristina M R
CEB-Centre of Biological Engineering, University of Minho, Campus de Gualtar, 4710-057 Braga, Portugal.
CISAS-Centro de Investigação e Desenvolvimento em Sistemas Agroalimentares e Sustentabilidade, Escola Superior de Tecnologia e Gestão, Instituto Politécnico de Viana do Castelo, Rua Escola Industrial e Comercial de Nun'Álvares, 4900-347 Viana do Castelo, Portugal.
Antioxidants (Basel). 2020 Apr 20;9(4):334. doi: 10.3390/antiox9040334.
Natural compounds from agro-food by-products have fostered interest in food industries. The aim of this study was to unravel potential uses for bark extracts (PBE). As functional features of this type of extracts are usually attributed to phenolic compounds, the extraction process was studied. Different PBEs were achieved, with high content in phenolic compounds, using different water/ethanol combinations as a solvent. These PBEs were chemically characterized, and their bioactivity and in vitro cell viability were evaluated. Extracts obtained with hydroethanolic solvents had higher content in phenolic and flavonoid compounds. All the PBEs presented high antioxidant, antibacterial and antihyperglycemic activities. Moreover, PBEs have low cytotoxicity and a selective activity against cancer cells as these were negatively affected. These features may allow the extracts to be used in food formulation and processing (as preservatives, antioxidants or bioactive ingredients), but they showed also potential for the pharmaceutical or nutraceutical sectors.
来自农业食品副产品的天然化合物引起了食品行业的关注。本研究的目的是揭示树皮提取物（PBE）的潜在用途。由于这类提取物的功能特性通常归因于酚类化合物，因此对提取过程进行了研究。使用不同的水/乙醇组合作为溶剂，获得了不同的PBE，其酚类化合物含量很高。对这些PBE进行了化学表征，并评估了它们的生物活性和体外细胞活力。用水醇混合溶剂获得的提取物中酚类和黄酮类化合物含量较高。所有PBE都具有高抗氧化、抗菌和抗高血糖活性。此外，PBE具有低细胞毒性，并且对癌细胞具有选择性活性，因为癌细胞受到了负面影响。这些特性可能使提取物可用于食品配方和加工（作为防腐剂、抗氧化剂或生物活性成分），但它们在制药或营养保健品领域也显示出潜力。
