Mascherini Gabriele, Tosi Benedetta, Giannelli Chiara, Ermini Elena, Osti Leonardo, Galanti Giorgio
Dipartimento di Medicina Sperimentale e Clinica, Università degli Studi di Firenze, 50134 Firenze, Italy.
J Funct Morphol Kinesiol. 2020 Jul 15;5(3):49. doi: 10.3390/jfmk5030049.
Improvements in cancer care over the years have increased the numbers of cancer survivors. Therefore, quality of life, fat mass management and physical activity are growing areas of interest in these people. After the surgical removal of a breast cancer, adjuvant therapy remains anyway a common strategy. The aim of this study was to assess how adjuvant therapy can affect the effectiveness of an unsupervised exercise program. Forty-two women were enrolled (52.0 ± 10.1 years). Assessments performed at baseline and after six months of exercise prescription were body composition, health-related quality of life, aerobic capacity by Six-Minute Walk Test, limbs strength by hand grip and chair test and flexibility by sit and reach. Statistical analyses were conducted by ANOVA tests and multiple regression. Improvements in body composition, physical fitness and quality of life (physical functioning, general health, social functioning and mental health items) were found. The percentage change in fat mass has been associated with adjuvant cancer therapy (intercept = -0.016; b = 8.629; < 0.05). An unsupervised exercise prescription program improves body composition, physical fitness and health-related quality of life in breast cancer survivors. Adjuvant therapy in cancer slows down the effectiveness of an exercise program in the loss of fat mass.
多年来癌症护理的改善增加了癌症幸存者的数量。因此，生活质量、体脂管理和身体活动成为这些人群中日益受到关注的领域。乳腺癌手术切除后，辅助治疗仍然是一种常见的策略。本研究的目的是评估辅助治疗如何影响无监督运动计划的效果。招募了42名女性（年龄52.0±10.1岁）。在基线和运动处方六个月后进行的评估包括身体成分、健康相关生活质量、通过六分钟步行测试评估的有氧能力、通过握力和椅子测试评估的肢体力量以及通过坐位体前屈评估的柔韧性。通过方差分析测试和多元回归进行统计分析。发现身体成分、身体素质和生活质量（身体功能、总体健康、社会功能和心理健康项目）有所改善。体脂百分比变化与辅助癌症治疗相关（截距=-0.016；b=8.629；<0.05）。无监督运动处方计划可改善乳腺癌幸存者的身体成分、身体素质和健康相关生活质量。癌症中的辅助治疗会减缓运动计划在减少体脂方面的效果。
