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帕金森病患者疾病分期的步态分析。

Analysis of Gait for Disease Stage in Patients with Parkinson's Disease.

机构信息

Research group HealthyFit, Institute of Health Research Galicia Sur (IISGS), Hospital University Complex of Pontevedra (CHOP), SERGAS, University of Vigo, 36310 Pontevedra, Spain.

出版信息

Int J Environ Res Public Health. 2021 Jan 15;18(2):720. doi: 10.3390/ijerph18020720.

Abstract

Understanding the motor patterns underlying the movement of individuals with Parkinson's disease (PD) is fundamental to the effective targeting of non-pharmacological therapies. This study aimed to analyze the gait pattern in relation to the evolutionary stages I-II and III-IV according to the Hoehn and Yahr (H&Y) scale in individuals affected by PD. The study was conducted with the participation of 37 PD patients with a mean age of 70.09 ± 9.53 years, and of whom 48.64% were women. The inclusion criteria were (1) to be diagnosed with PD; (2) to be in an evolutionary stage of the disease between I and IV: and (3) to be able to walk independently and without any assistance. Kinematic and spatial-temporal parameters of the gait were analyzed. The results showed differences in speed of movement, cadence, stride length, support duration, swing duration, step width, walking cycle duration, and double support time between the stages analyzed. These results confirmed the differences in PD gait pattern between stages I-II and III-IV. Different behaviors of the same variable were recorded depending on whether the right or left side was affected by PD.

摘要

了解帕金森病(PD)患者运动的运动模式对于非药物治疗的有效靶向至关重要。本研究旨在根据 Hoehn 和 Yahr(H&Y)量表分析与疾病进化阶段 I-II 和 III-IV 相关的步态模式。该研究共纳入 37 名平均年龄为 70.09 ± 9.53 岁的 PD 患者,其中 48.64%为女性。纳入标准为:(1)被诊断为 PD;(2)疾病处于 I-IV 阶段;(3)能够独立行走,无需任何帮助。对步态的运动学和时空参数进行了分析。结果显示,分析的阶段之间在运动速度、步频、步长、支撑时间、摆动时间、步宽、行走周期时间和双支撑时间方面存在差异。这些结果证实了 PD 步态模式在 I-II 和 III-IV 阶段之间存在差异。根据 PD 是否影响右侧或左侧,记录了同一变量的不同行为。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1573/7830506/8ec40c03656b/ijerph-18-00720-g001.jpg

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