Vanhelst Jérémy, Béghin Laurent, Turck Dominique, Labreuche Julien, Coopman Stéphanie, Gottrand Frédéric, Ley Delphine
Univ. Lille, Inserm, CHU Lille, U1286 - INFINITE - Institute for Translational Research in Inflammation, 59000, Lille, France.
CIC 1403 - Clinical Investigation Center, CHU Lille, 59000, Lille, France.
Pediatr Res. 2021 Oct;90(4):847-852. doi: 10.1038/s41390-020-01313-5. Epub 2021 Jan 19.
The aim of this study was to assess PA patterns among children and adolescents with inflammatory bowel disease (IBD).
Sixty participants with IBD (42 Crohn's disease [CD], 10 ulcerative colitis [UC], and 8 IBD-unclassified [IBD-U], 30 male patients) in remission (n = 45) or with mild disease (n = 15) were compared with 60 healthy age- and sex-matched controls. Each participant wore a triaxial accelerometer during 4 consecutive days for objective daily PA quantification.
Overall, there was no significant difference in daily PA patterns between patients with IBD and healthy controls, with 31.7% of patients with IBD and 38.3% of healthy controls fulfilling the recommendation of 60 min of moderate-to-vigorous physical activity (MVPA) daily (NS). Male patients with IBD spent significantly less time in MVPA compared with matched healthy controls (mean difference, 16.2 min day; p < 0.05). No difference was observed for female patients with IBD. No difference in sedentary pattern between male patients with IBD and controls was found.
Children and adolescents with inactive or mildly active IBD have similar PA patterns compared with healthy controls, except for male patients who have reduced moderate-to-vigorous PA. By far, most patients with IBD do not fulfill the MVPA recommendations for health benefits.
There is few data on PA patterns in pediatric patients with IBD. Methodological issues to assess PA limit the strengths of these studies. Pediatric IBD patients with inactive or mildly active IBD have similar physical activity patterns compared with healthy controls, except for male patients who have reduced moderate-to-vigorous PA. Most patients with IBD do not fulfill the MVPA recommendations for health benefits.
本研究旨在评估炎症性肠病（IBD）患儿及青少年的身体活动（PA）模式。
将60例缓解期（n = 45）或轻度疾病期（n = 15）的IBD患者（42例克罗恩病[CD]、10例溃疡性结肠炎[UC]和8例未分类IBD[IBD-U]，30例男性患者）与60例年龄和性别匹配的健康对照者进行比较。每位参与者连续4天佩戴三轴加速度计，以客观量化每日的PA。
总体而言，IBD患者与健康对照者的每日PA模式无显著差异，31.7%的IBD患者和38.3%的健康对照者达到了每日60分钟中等至剧烈身体活动（MVPA）的建议（无显著性差异）。与匹配的健康对照者相比，IBD男性患者在MVPA上花费的时间显著更少（平均差异为每天16.2分钟；p < 0.05）。IBD女性患者未观察到差异。IBD男性患者与对照者在久坐模式上未发现差异。
除了中度至剧烈PA减少的男性患者外，非活动期或轻度活动期IBD的儿童和青少年与健康对照者具有相似的PA模式。到目前为止，大多数IBD患者未达到对健康有益的MVPA建议。
关于IBD儿科患者PA模式的数据很少。评估PA的方法学问题限制了这些研究的力度。除了中度至剧烈PA减少的男性患者外，非活动期或轻度活动期IBD的儿科患者与健康对照者具有相似的身体活动模式。大多数IBD患者未达到对健康有益的MVPA建议。
