Referral Center for Pediatric Gastroenterology and Nutrition, Children's Hospital Zagreb, Zagreb, Croatia.
School of Medicine, University of Zagreb, Zagreb, Croatia.
Pediatr Int. 2024 Jan-Dec;66(1):e15788. doi: 10.1111/ped.15788.
The aim of our study was to investigate the effect of an exercise program on health-related quality of life (HRQoL) and sleep quality in children with inflammatory bowel disease (IBD) in remission.
A total of 42 pediatric IBD patients in remission were recruited to participate in a 6-month-long home-based exercise program. Their mean age was 15.3 years (with a range of ± 2.08 years) and there were 25 boys. With regard to disease type, 22 had Crohn's disease (CD), 18 had ulcerative colitis (UC), and two had unclassified inflammatory bowel disease (IBD-U). Prior to starting the program, and after its completion, HRQoL was assessed using the IMPACT III questionnaire, and sleep quality was assessed using the Pittsburgh Sleep Quality Index (PSQI) questionnaire. Patients also wore a triaxial accelerometer for 5 consecutive days before and after the completion of the exercise program to assess physical activity (PA) objectively.
Study participants experienced no significant increase in their IMPACT III score (from 147.6 ± 2.7 to 149.6 ± 2.7, p = 0.106) following the completion of the exercise program. The prevalence of impaired sleep quality (PSQI > 5) decreased significantly from 30.9 to 23.8% (p = 0.027). At the baseline, participants' time spent in light PA (LPA) correlated positively with their IMPACT III score (coefficient (coef.) 0.398, p = 0.013). Following the completion of the resistance training program, the changes in the IMPACT III score correlated positively with time spent in moderate-to-vigorous PA (MVPA) (coef. 0.329, p = 0.047) and negatively with changes in PSQI score (coef. -0.493, p = 0.001).
The number of children with impaired sleep quality decreased significantly following the completion of a 6-month-long home-based resistance training program but improvements in HRQoL scores did not reach statistical significance.
我们的研究目的是探讨运动方案对缓解期炎症性肠病（IBD）儿童的健康相关生活质量（HRQoL）和睡眠质量的影响。
共招募 42 名缓解期的儿科 IBD 患者参与为期 6 个月的家庭运动方案。他们的平均年龄为 15.3 岁（范围为±2.08 岁），其中 25 名男性。根据疾病类型，22 例为克罗恩病（CD），18 例为溃疡性结肠炎（UC），2 例为未分类炎症性肠病（IBD-U）。在开始该方案之前和完成之后，使用 IMPACT III 问卷评估 HRQoL，使用匹兹堡睡眠质量指数（PSQI）问卷评估睡眠质量。在完成运动方案之前和之后，患者还佩戴三轴加速度计连续 5 天，以客观评估身体活动（PA）。
研究参与者在完成运动方案后，IMPACT III 评分无显著升高（从 147.6±2.7 增至 149.6±2.7，p=0.106）。睡眠质量受损（PSQI＞5）的患病率从 30.9%显著降至 23.8%（p=0.027）。在基线时，参与者的轻体力活动（LPA）时间与 IMPACT III 评分呈正相关（系数 0.398，p=0.013）。在完成抗阻训练方案后，IMPACT III 评分的变化与中高强度体力活动（MVPA）时间呈正相关（系数 0.329，p=0.047），与 PSQI 评分的变化呈负相关（系数-0.493，p=0.001）。
完成为期 6 个月的家庭抗阻训练方案后，睡眠质量受损的儿童数量显著减少，但 HRQoL 评分的改善未达到统计学意义。
