Wang S, Grubbs P E, Basu S, Robertazzi R R, Thomsen S, Rose D M, Jacobowitz I J, Cunningham J N
Department of Cardiovascular Surgery, Maimonides Medical Center, Brooklyn, New York 11219.
Microsurgery. 1988;9(1):10-3. doi: 10.1002/micr.1920090104.
This experiment evaluated the influence of blood on the weld strength of laser-assisted microvascular anastomoses (LAMA). Rat femoral arteries were anastomosed end-to-end by either direct laser welding (group I) or by a blood-bonded technique (group II) whereby fresh blood was applied to the vessel edges before laser exposure. Bursting strength was measured at 0, 1, and 24 hours and at 3 and 7 days by infusing methylene blue into the vessel while pressure was monitored. The results showed significantly increased bursting strength in group II compared with group I at 0 hour and 7 days (P less than 0.05). There was a significant increase in bursting strength in group I from 0 hour to 1 hour (P less than 0.05). It is concluded that blood-bonding enhances the early bursting strength of LAMAs and may facilitate arterial wall healing.
本实验评估了血液对激光辅助微血管吻合术（LAMA）焊接强度的影响。将大鼠股动脉端端吻合，其中一组采用直接激光焊接（第一组），另一组采用血液黏合技术（第二组），即在激光照射前将新鲜血液涂抹于血管边缘。在0小时、1小时、24小时以及3天和7天时，通过在监测压力的同时向血管内注入亚甲蓝来测量破裂强度。结果显示，与第一组相比，第二组在0小时和7天时的破裂强度显著增加（P小于0.05）。第一组在从0小时到1小时时破裂强度显著增加（P小于0.05）。得出的结论是，血液黏合可增强激光辅助微血管吻合术的早期破裂强度，并可能促进动脉壁愈合。
