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圆锥角膜、眼部过敏与睡眠行为的相关性。

Association between keratoconus, ocular allergy, and sleeping behavior.

机构信息

Department of Ophthalmology and Visual Sciences, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, SP, Brazil.

出版信息

Arq Bras Oftalmol. 2021 Jan-Feb;84(1):17-21. doi: 10.5935/0004-2749.20210003.

DOI:10.5935/0004-2749.20210003
PMID:33470337
Abstract

PURPOSE

To compare the severity and laterality of keratoconus according to allergic rhinitis, scratching and sleeping habits, and manual dexterity.

METHODS

Objective assessments regarding allergic rhinitis, eye itching, and slee-ping position among patients with keratoconus (diagnosed based on corneal tomography) were conducted. Diagnostic criteria and classification were based on the Amsler-Krumeich classification.

RESULTS

Ocular pruritus was reported by 29 of 34 participants (85.29%). Eighteen participants (62.07%) reported equal scratching of both eyes, six (20.69%) more on the right eye, and five (17.24%) more on the left eye. Comparison of the main sleeping position and the eye with more severe presentation of the disease using Fisher's exact test revealed some correlations (0.567 and 0.568 in the right and left eye, respectively). However, these correlations were not statistically significant.

CONCLUSIONS

The association between higher keratometry values and sleeping position appears to be more significant than that reported between keratometry and itching, or manual dexterity.

摘要

目的

比较根据变应性鼻炎、搔抓和睡眠习惯以及手灵巧度,圆锥角膜的严重程度和偏侧性。

方法

对圆锥角膜患者(根据角膜断层扫描诊断)进行变应性鼻炎、眼痒和睡眠姿势的客观评估。诊断标准和分类基于 Amsler-Krumeich 分类。

结果

34 名参与者中有 29 名(85.29%)报告有眼部瘙痒。18 名参与者(62.07%)报告双眼搔抓程度相等,6 名(20.69%)右眼搔抓更重,5 名(17.24%)左眼搔抓更重。使用 Fisher 精确检验比较主要睡眠姿势和疾病表现更严重的眼睛,发现存在一些相关性(右眼和左眼分别为 0.567 和 0.568)。然而,这些相关性没有统计学意义。

结论

角膜曲率计值与睡眠姿势之间的关联似乎比角膜曲率计值与瘙痒或手灵巧度之间的关联更显著。

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本文引用的文献

1
Obstructive Sleep Apnea Assessed by Overnight Polysomnography in Patients With Keratoconus.圆锥角膜患者夜间多导睡眠图评估阻塞性睡眠呼吸暂停
Cornea. 2018 Apr;37(4):470-473. doi: 10.1097/ICO.0000000000001509.
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Effect of Sleep Position on the Ocular Surface.睡眠姿势对眼表的影响。
Cornea. 2017 May;36(5):567-571. doi: 10.1097/ICO.0000000000001167.
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The association of sleep quality with dry eye disease: the Osaka study.睡眠质量与干眼症的关联:大阪研究
光性折射性角膜切除术术后角膜扩张:共聚焦显微镜病例报告及文献复习。
Arq Bras Oftalmol. 2023 Oct 13;87(6):e20210296. doi: 10.5935/0004-2749.2021-0296. eCollection 2023.
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Comparison of corneal measurements in normal and keratoconus eyes using Anterior Segment Optical Coherence Tomography (AS-OCT) and Pentacam HR topographer.使用眼前节光学相干断层扫描(AS-OCT)和 Pentacam HR 地形图比较正常眼和圆锥角膜眼中的角膜测量值。
BMC Ophthalmol. 2023 May 3;23(1):194. doi: 10.1186/s12886-023-02946-w.
Clin Ophthalmol. 2016 Jun 1;10:1015-21. doi: 10.2147/OPTH.S99620. eCollection 2016.
4
Eye rubbing type and prevalence including contact lens 'removal-relief' rubbing.揉眼类型及患病率,包括隐形眼镜“摘除-缓解”性揉眼。
Clin Exp Optom. 2016 Jul;99(4):366-72. doi: 10.1111/cxo.12343. Epub 2016 Jun 16.
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Global Consensus on Keratoconus Diagnosis.圆锥角膜诊断的全球共识
Cornea. 2015 Dec;34(12):e38-9. doi: 10.1097/ICO.0000000000000623.
6
Risk factors for keratoconus in Israel: a case-control study.以色列圆锥角膜的危险因素:一项病例对照研究。
Ophthalmic Physiol Opt. 2015 Nov;35(6):673-81. doi: 10.1111/opo.12237. Epub 2015 Aug 18.
7
Cytokine Expression in Keratoconus and its Corneal Microenvironment: A Systematic Review.圆锥角膜及其角膜微环境中的细胞因子表达:一项系统综述
Ocul Surf. 2015 Oct;13(4):272-83. doi: 10.1016/j.jtos.2015.04.006. Epub 2015 Jul 30.
8
The genetic and environmental factors for keratoconus.圆锥角膜的遗传和环境因素。
Biomed Res Int. 2015;2015:795738. doi: 10.1155/2015/795738. Epub 2015 May 17.
9
Keratoconus: an inflammatory disorder?圆锥角膜:一种炎症性疾病?
Eye (Lond). 2015 Jul;29(7):843-59. doi: 10.1038/eye.2015.63. Epub 2015 May 1.
10
Elevated expression of matrix metalloproteinase-9 and inflammatory cytokines in keratoconus patients is inhibited by cyclosporine A.角膜膨隆症患者的基质金属蛋白酶-9 和炎症细胞因子表达升高,环孢素 A 可抑制其表达。
Invest Ophthalmol Vis Sci. 2015 Feb 3;56(2):738-50. doi: 10.1167/iovs.14-14831.