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乙型肝炎病毒感染的血清流行率:尼日利亚一大群卫生保健工作者的横断面研究。

Sero-prevalence of Hepatitis B virus infection: A cross-sectional study of a large population of health care workers in Nigeria.

机构信息

Department of Medicine, College of Medicine, University of Nigeria, Ituku-Ozalla Campus, Enugu State, Nigeria.

Department of Chemical Pathology, College of Medicine, University of Nigeria, Ituku-Ozalla Campus, Enugu State, Nigeria.

出版信息

Niger J Clin Pract. 2021 Jan;24(1):38-44. doi: 10.4103/njcp.njcp_671_19.

Abstract

BACKGROUND

Hepatitis B virus (HBV) infection has been recognized globally as a major public health challenge necessitating a global call for increased awareness, patients' identification, and development of activities for prevention and control of the disease. Consequently, massive health education campaigns and screening exercises have been mounted globally to mark the World Hepatitis Day (WHD).

AIMS

As part of WHD 2016 activities, we undertook a survey and screening of health care workers in order to raise awareness, identify patients and contribute to the Global Health Strategy goal of eliminating HBV infection by the year 2030.

METHOD

This was a cross-sectional analytical study done at the University of Nigeria Teaching Hospital, Ituku-Ozalla, Enugu, Nigeria. Hospital workers voluntarily presented themselves to be screened using a rapid test kit and completing a semi-structured investigator-administered questionnaire.

RESULTS

A total of 3123 participants were studied. The mean age of the participants was 39.4 ± 9.6 years. The seroprevalence of HBV infection was 2.3%. Most (97.0%) of the participants had previously heard about HBV infection and over two thirds (68.1%) could correctly identify risk factors and modes of transmission of HBV. Twenty-eight and a half percent of the participants knew their hepatitis B virus status prior to the study.

CONCLUSION

The seroprevalence of HBV among healthcare workers in Enugu, Nigeria is relatively low compared to figures from other African countries. The healthcare workers have considerable knowledge of the disease. However, the observed knowledge gaps in awareness and screening need to be addressed.

摘要

背景

乙型肝炎病毒 (HBV) 感染已在全球范围内被视为一项重大公共卫生挑战,需要全球提高认识、发现患者,并开展预防和控制该疾病的活动。因此,全球范围内开展了大规模的健康教育运动和筛查活动来纪念世界肝炎日 (WHD)。

目的

作为 2016 年 WHD 活动的一部分,我们对医护人员进行了调查和筛查,以提高认识、发现患者,并为 2030 年消除 HBV 感染的全球卫生战略目标做出贡献。

方法

这是在尼日利亚埃努古州伊图库-奥扎拉的尼日利亚大学教学医院进行的一项横断面分析研究。医院工作人员自愿使用快速检测试剂盒并填写半结构式调查员管理问卷进行筛查。

结果

共研究了 3123 名参与者。参与者的平均年龄为 39.4 ± 9.6 岁。HBV 感染的血清流行率为 2.3%。大多数(97.0%)参与者之前听说过 HBV 感染,超过三分之二(68.1%)能够正确识别 HBV 的危险因素和传播途径。28.5%的参与者在研究前知道自己的乙型肝炎病毒状况。

结论

与其他非洲国家的数据相比,尼日利亚埃努古的医护人员中 HBV 的血清流行率相对较低。医护人员对该疾病有相当的了解。然而,观察到的认识和筛查方面的知识差距需要得到解决。

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