Patel Shruti R, Zayas Jacqueline, Medina-Inojosa Jose R, Loprinzi Charles, Cathcart-Rake Elizabeth J, Bhagra Anjali, Olson Janet E, Couch Fergus J, Ruddy Kathryn J
Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota.
Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Medicine and the Mayo Clinic Medical Scientist Training Program, Rochester, Minnesota.
Glob Adv Health Med. 2021 Jan 8;10:2164956120984140. doi: 10.1177/2164956120984140. eCollection 2021.
Integrative therapies such as yoga are potential treatments for many psychological and physical symptoms that occur during and/or after treatment for cancer. The purpose of the current study was to evaluate the patient-perceived benefit of yoga for symptoms commonly experienced by breast cancer survivors.
1,049 breast cancer survivors who had self-reported use of yoga on a follow up survey, in an ongoing prospective Mayo Clinic Breast Disease Registry (MCBDR), received an additional mailed yoga-focused survey asking about the impact of yoga on a variety of symptoms. Differences between pre- and post- scores were assessed using Wilcoxon Signed Rank Test.
802/1,049 (76%) of women who were approached to participate, consented and returned the survey. 507/802 (63%) reported use of yoga during and/or after their cancer diagnosis. The vast majority of respondents (89.4%) reported some symptomatic benefit from yoga. The most common symptoms that prompted the use of yoga were breast/chest wall pain, lymphedema, and anxiety. Only 9% of patients reported that they had been referred to yoga by a medical professional. While the greatest symptom improvement was reported with breast/chest wall pain and anxiety, significant improvement was also perceived in joint pain, muscle pain, fatigue, headache, quality of life, hot flashes, nausea/vomiting, depression, insomnia, lymphedema, and peripheral neuropathy, (all p-values <0.004).
Data supporting the use of yoga for symptom management after cancer are limited and typically focus on mental health. In this study, users of yoga often reported physical benefits as well as mental health benefits. Further prospective studies investigating the efficacy of yoga in survivorship are warranted.
诸如瑜伽之类的综合疗法对于癌症治疗期间和/或之后出现的许多心理和身体症状而言是潜在的治疗方法。本研究的目的是评估乳腺癌幸存者普遍经历的症状中,患者所感知到的瑜伽的益处。
在一项正在进行的前瞻性梅奥诊所乳腺疾病登记研究(MCBDR)中,1049名在随访调查中自我报告使用过瑜伽的乳腺癌幸存者收到了一份额外邮寄的、聚焦于瑜伽的调查问卷,询问瑜伽对各种症状的影响。使用Wilcoxon符号秩和检验评估前后得分的差异。
受邀参与的1049名女性中,802名(76%)同意并返回了调查问卷。507名(63%)报告在癌症诊断期间和/或之后使用过瑜伽。绝大多数受访者(89.4%)报告从瑜伽中获得了一些症状改善。促使使用瑜伽的最常见症状是乳房/胸壁疼痛、淋巴水肿和焦虑。只有9%的患者报告他们是由医疗专业人员推荐去做瑜伽的。虽然乳房/胸壁疼痛和焦虑的症状改善最为显著,但关节疼痛、肌肉疼痛、疲劳、头痛、生活质量、潮热、恶心/呕吐、抑郁、失眠、淋巴水肿和周围神经病变也有显著改善(所有p值<0.004)。
支持癌症后使用瑜伽进行症状管理的数据有限,且通常侧重于心理健康。在本研究中,瑜伽使用者经常报告身体和心理健康方面的益处。有必要进一步开展前瞻性研究,调查瑜伽在癌症幸存者中的疗效。