Krumholz A, Stern B J, Weiss H D
Division of Neurology, Sinai Hospital of Baltimore, MD 21215.
Neurology. 1988 Mar;38(3):401-5. doi: 10.1212/wnl.38.3.401.
We studied the effect of seizures and myoclonus following cardiopulmonary resuscitation (CPR) on the outcome of all comatose adult survivors of CPR over an 8-year period. Either seizures or myoclonus occurred in 50 of 114 patients (44%): seizures in 41 patients (36%) and myoclonus in 40 (35%). Status epilepticus or status myoclonus occurred in 36 patients (32%), and 19 (17%) had myoclonic status epilepticus (MSE). Seizures and myoclonus per se were not significantly related to outcome, but status epilepticus, status myoclonus, and, particularly, MSE were predictive of poor outcome as judged by survival and recovery of consciousness.
我们研究了心肺复苏（CPR）后癫痫发作和肌阵挛对8年间所有成年CPR昏迷幸存者结局的影响。114例患者中有50例（44%）出现癫痫发作或肌阵挛：41例患者（36%）出现癫痫发作，40例（35%）出现肌阵挛。36例患者（32%）出现癫痫持续状态或肌阵挛持续状态，19例（17%）出现肌阵挛性癫痫持续状态（MSE）。癫痫发作和肌阵挛本身与结局无显著相关性，但癫痫持续状态、肌阵挛持续状态，尤其是MSE，根据生存和意识恢复情况判断，可预测预后不良。
