Tam Emily W T, Tsang Chi-Ching, Lau Susanna K P, Woo Patrick C Y
Department of Microbiology, The University of Hong Kong, Hong Kong.
State Key Laboratory of Emerging Infectious Diseases, The University of Hong Kong, Hong Kong.
Mitochondrial DNA B Resour. 2017 Jan 4;1(1):941-942. doi: 10.1080/23802359.2016.1261610.
We report the complete mitochondrial DNA (mtDNA) sequences of four strains and performed comparative genomic and phylogenetic analyses. The gene orders of the four mtDNAs are identical to the previously published mtDNA of strain PM1 (, , , , , , , , , , , ). Phylogenetic analysis showed that the four mtDNAs were clustered with that of PM1 with high bootstrap support. Compared to mtDNA of PM1, the only non-synonymous mutation was located in (T505M) of strain PM26. Synonymous single nucleotide polymorphisms were observed at eight positions in the four mtDNAs.
我们报告了四个菌株的完整线粒体DNA(mtDNA)序列,并进行了比较基因组学和系统发育分析。这四个mtDNA的基因顺序与之前发表的PM1菌株的mtDNA相同(,,,,,,,,,,,)。系统发育分析表明,这四个mtDNA在高自展支持下与PM1的mtDNA聚类在一起。与PM1的mtDNA相比,唯一的非同义突变位于PM26菌株的(T505M)。在这四个mtDNA的八个位置观察到同义单核苷酸多态性。