是……中镶嵌眼表型的非致死修饰因子。

is a non-lethal modifier of the mosaic eye phenotype in .

作者信息

Vrailas-Mortimer Alysia D, Aggarwal Nitish, Ahmed Neha N, Alberts Ian M, Alhawasli Masa, Aljerdi Ibrahim A, Allen Brooke M, Alnajar Ahmad M, Anderson Michael A, Armstong Ryan, Avery Chace C, Avila Eric J, Baker Tyra N, Basardeh Soolmaz, Bates Natasha A, Beidas Farrah N, Bosler Ashton C, Brewer Deja M, Buenaventura Ryan S, Burrell Natalie Jl, Cabrera-Lopez Alyn P, Cervantes-Gonzalez Amairani B, Cezar Raymond P, Coronel Joselyn, Croslyn Corinne, Damery Konnor R, Diaz-Alavez Lucero, Dixit Nupur P, Duarte Dilcia L, Emke Amanda R, English Katherine, Eshun Audrey A, Esterly Samuel R, Estrada Arnold J, Feng Mark, Freund Meghan M, Garcia Niko, Ghotra Charandeep S, Ghyasi Haddia, Hale Christa Sa, Hulsman Luci, Jamerson Lindsey, Jones Austin K, Kuczynski Madeline, Lacey-Kennedy Takailah N, Lee Mindy J, Mahjoub Tala, Mersinger Molly C, Muckerheide Alyssa D, Myers David W, Nielsen Karen, Nosowicz Paul J, Nunez Jacinda A, Ortiz Amy C, Patel Tulsi T, Perry Natalie N, Poser W Storm A, Puga Deisy M, Quam Cathrine, Quintana-Lopez Paulina, Rennerfeldt Piper, Reyes Nicholas M, Rines Ian G, Roberts Cally, Robinson Daniel B, Rossa Kalina M, Ruhlmann Gloria J, Schmidt Jeremy, Sherwood John R, Shonoda Dimyana H, Soellner Hannah, Torrez Juan C, Velide Mayukah, Weinzapfel Zachary, Ward Alisa C, Bieser Kayla L, Merkle Julie A, Stamm Joyce C, Tillett Richard L, Kagey Jacob D

机构信息

Illinois State University, Normal, IL USA.

University of Detroit Mercy, Detroit, MI USA.

出版信息

MicroPubl Biol. 2021 Jan 18;2021. doi: 10.17912/micropub.biology.000359.

DOI:10.17912/micropub.biology.000359

PMID:33474526

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7812380/

Abstract

Genetic screens have been used to identify genes involved in the regulation of different biological processes. We identified growth mutants in a Flp/FRT screen using the eye to identify conditional regulators of cell growth and cell division. One mutant identified from this screen, , was mapped and characterized by researchers in undergraduate genetics labs as part of the Fly-CURE. We find that is a non-lethal genetic modifier of the mosaic eye phenotype.

摘要

遗传筛选已被用于识别参与不同生物过程调控的基因。我们在一个Flp/FRT筛选中利用眼睛来识别细胞生长和细胞分裂的条件调节因子，从而鉴定出生长突变体。在这个筛选中鉴定出的一个突变体，由本科遗传学实验室的研究人员作为Fly-CURE的一部分进行了定位和表征。我们发现，该突变体是镶嵌眼表型的一个非致死性遗传修饰因子。