是基因（）在中的一个新等位基因。（你原文中部分括号内容缺失，以上翻译根据现有内容尽可能完善了）

is a novel allele of the gene ( ) in .

作者信息

Chammout Hanadi, Adkins Delia L, Al-Olimat Aleece K, Alsaad Zeinab, Altopp Beatrice M, Amer Tuqa, Apampa Feyi O, Avery Gwendolyn R, Bazzi Isaac I, Beck Emilia D, Beier Elise L, Belisle B Shafer, Benton Lane, Bolyard Madison M, Brain Olivia E, Buckner Eldon T, Chowdhury Shria Roy, Cifranic Jennifer R, Cleary Liam, Clum Tyler R, Cruz Autumn M, DeGray Meghan V, Echeverry Isabel L, El Dana Haya, Elkadri Sarah K, Estep Paige L, Falke Luke R, Foor Hannah J, Gullapalli Anika S, Hakim Sandro S, Hazime Hussein B, Heininger Lauren E, Hoeft Emma G, James Lauren M, Jeon Yeowon, Johnson Megan R, Jordan Laine P, Khan Zayd, Kochensparger Sydney K, Koria Fadi J, Krasnow Ruby M, Lilly Veronica, Lim Eileen, MacCormack Ian T, Malesh Andriy, Mariano Mikayla G, Mentzer Audrey C, Messner Katelyn H, Myers Katlyn C, Newman Emily R, Richters Annie M, Romero Liliana, Rotem Adam, Saho Reese J, Sawaki Kaname, Selders Ashley N, Shockney Elizabeth, Sobh Farah A, Speiser Isabelle F, Sproul Breanna M, Sroufe Veronica J, Tollkuci Antonia, Trevino Cassandra C, Vapenik Megan A, Wagner Erin M, Bieser Kayla L, Siders Jamie L, Thackeray Justin R, Kagey Jacob D

机构信息

University of Detroit Mercy, Detroit, Michigan, United States.

Ohio Northern University, Ada, Ohio, United States.

出版信息

MicroPubl Biol. 2024 Sep 26;2024. doi: 10.17912/micropub.biology.001290. eCollection 2024.

DOI:10.17912/micropub.biology.001290

PMID:39399787

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11467748/

Abstract

Genetic screens in have long been used to identify genes found in a variety of developmental, cellular, and behavioral processes. Here we describe the characterization and mapping of a mutation identified in a conditional screen for genetic regulators of cell growth and cell division. Within a Flp/FRT system, mutant results in a reduction of mutant tissue and a rough eye phenotype. We find that maps to the gene , providing further support that is a critical gene in eye development. This mutant was characterized, mapped and sequenced by undergraduate students within the Fly-CURE consortium.

摘要

长期以来，在[具体研究对象]中进行的遗传筛选一直被用于识别在各种发育、细胞和行为过程中发现的基因。在此，我们描述了在细胞生长和细胞分裂的遗传调控因子的条件性筛选中鉴定出的一个突变的特征和定位。在一个Flp/FRT系统中，突变体导致突变组织减少和粗糙眼表型。我们发现该突变体定位到基因[具体基因名称]，这进一步支持了[具体基因名称]是[具体生物名称]眼睛发育中的关键基因。这个突变体由Fly-CURE联盟的本科生进行了特征分析、定位和测序。