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蓖麻单分支支架移植物植入术治疗B型急性主动脉夹层的疗效与安全性:一项回顾性分析

The efficacy and safety of castor single-branch stent graft implantation in the treatment of type B acute aortic dissection: a retrospective analysis.

作者信息

Liu Shangdian, Sun Zhengyang, Qin Jinjin, Dong Yifei, Luo Bin

机构信息

Department of Cardiovascular Surgery, Shenzhen Baoan People's Hospital, Shenzhen, China.

出版信息

J Thorac Dis. 2025 Jun 30;17(6):3762-3771. doi: 10.21037/jtd-2024-2102. Epub 2025 Jun 10.

Abstract

BACKGROUND

Acute type B aortic dissection requires timely and effective treatment. With recent focus on evaluating the comparative efficacy and safety of novel Castor single-branch covered-stent implantation, this study investigated the efficacy and safety of Castor single-branch covered-stent implantation in the treatment of acute type B aortic dissection, aiming to provide treatment option for patients with acute type B aortic dissection.

METHODS

Clinical data of 73 patients with acute type B aortic dissection (January 2020 to November 2021) were retrospectively analyzed. Patients were divided into control [undergoing thoracic endovascular aortic repair (TEVAR), 35 cases] and Castor single-branch covered-stent implantation surgery (38 cases) groups. Baseline data, early postoperative recovery indicators, incidence of early postoperative complications and mortality, long-term prognosis, long-term efficacy, and changes in aortic diameter before and after surgery were compared.

RESULTS

Castor single-branch covered-stent implantation surgery group had significantly shorter intensive care unit (ICU) stay (P=0.03), postoperative hospital stay (P=0.01), total hospital stay (P=0.008), total complication rate (P=0.03) compared to the control group. The number of patients requiring secondary intervention (P=0.01) and formation of new intimal tears at the stent edges (P=0.02) was significantly higher in the control group, whereas proportion of stents in position was lower (P=0.01). In the Castor single-branch covered-stent implantation surgery group, number of patients whose condition improved was significantly higher (P=0.046), and the descending aortic diameter postoperatively was longer (P<0.001).

CONCLUSIONS

Castor single-branch stent graft implantation appears to offer advantages in terms of early postoperative recovery, lower complication rates, and improved long-term prognosis and effectiveness.

摘要

背景

急性B型主动脉夹层需要及时有效的治疗。随着近期对新型Castor单分支覆膜支架植入术的比较疗效和安全性评估的关注,本研究探讨了Castor单分支覆膜支架植入术治疗急性B型主动脉夹层的疗效和安全性,旨在为急性B型主动脉夹层患者提供治疗选择。

方法

回顾性分析2020年1月至2021年11月期间73例急性B型主动脉夹层患者的临床资料。患者分为对照组[接受胸主动脉腔内修复术(TEVAR),35例]和Castor单分支覆膜支架植入手术组(38例)。比较两组的基线数据、术后早期恢复指标、术后早期并发症发生率和死亡率、长期预后、长期疗效以及手术前后主动脉直径的变化。

结果

与对照组相比,Castor单分支覆膜支架植入手术组的重症监护病房(ICU)住院时间(P = 0.03)、术后住院时间(P = 0.01)、总住院时间(P = 0.008)和总并发症发生率(P = 0.03)显著缩短。对照组需要二次干预的患者数量(P = 0.01)和支架边缘新内膜撕裂的形成率(P = 0.02)显著更高,而支架在位比例更低(P = 0.01)。在Castor单分支覆膜支架植入手术组中,病情改善的患者数量显著更多(P = 0.046),术后降主动脉直径更长(P < 0.001)。

结论

Castor单分支覆膜支架植入术在术后早期恢复、较低的并发症发生率以及改善长期预后和有效性方面似乎具有优势。

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