中国大陆青少年牙周病的流行病学：1983-2020 年的系统评价和荟萃分析。

Epidemiology of periodontal disease in adolescents in mainland China, 1983-2020: a systematic review and meta-analysis.

机构信息

College of Stomatology, Chongqing Medical University, Chongqing, China; Chongqing Key Laboratory of Oral Diseases and Biomedical Sciences, Chongqing, China; Chongqing Municipal Key Laboratory of Oral Biomedical Engineering of Higher Education, Chongqing, China; The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.

出版信息

Ann Palliat Med. 2021 Jan;10(1):45-60. doi: 10.21037/apm-20-1919. Epub 2021 Jan 18.

DOI:10.21037/apm-20-1919

PMID:33474964

Abstract

BACKGROUND

Periodontal disease is a chronic inflammatory disease that includes primarily gingivitis and periodontitis, caused by bacterial infection of the supporting structures of the teeth. For years, much attention has been diverted to periodontal disease among the elderly, not enough attention is paid to adolescents. The purpose of this meta-analysis is to evaluate the epidemic trend of periodontal disease in adolescents in mainland China.

METHODS

We conducted a comprehensive literature search through PubMed, Embase, CNKI, Chongqing VIP database, Chinese Wan Fang Database, and CBM. A series of subgroup analyses were done to explore the epidemiological characteristics of periodontal disease (gender, location, age, survey year, and geographical distribution) with the help of related software.

RESULTS

Thirty studies were included in this study. The data extraction and analysis were from three indexes, including bleeding on probing (BOP), pocket depth (PD), and dental calculus (DC). The detection rates of BOP(+), PD ≥4 mm and DC(+) were 48.8% (95% CI: 36.2-61.4%), 1.0% (0.0-2.0%), and 49.8% (41.0-58.6%), respectively. There were significant differences for the prevalence of gingivitis both in gender and area: the prevalence was higher in males than that in females, and risk ratio was 1.04 (95% CI, 1.01-1.06); a lower prevalence in urban areas compared with rural areas, and the risk ratio was 0.90 (95% CI, 0.85-0.96).

CONCLUSIONS

This study shows a high prevalence of gingivitis among adolescents in China. Higher-quality epidemiological surveys with standard examination criteria are needed.

摘要

背景

牙周病是一种慢性炎症性疾病，主要包括牙龈炎和牙周炎，由牙齿支持结构的细菌感染引起。多年来，人们对老年人的牙周病给予了很多关注，但对青少年的关注却不够。本荟萃分析的目的是评估中国大陆青少年牙周病的流行趋势。

方法

我们通过 PubMed、Embase、CNKI、重庆 VIP 数据库、中国万方数据库和 CBM 进行了全面的文献检索。借助相关软件，进行了一系列亚组分析，以探讨牙周病的流行病学特征（性别、地点、年龄、调查年份和地理分布）。

结果

本研究共纳入 30 项研究。数据提取和分析来自三个指标，包括探诊出血（BOP）、牙周袋深度（PD）和牙石（DC）。BOP（+）、PD≥4mm 和 DC（+）的检出率分别为 48.8%（95%CI：36.2-61.4%）、1.0%（0.0-2.0%）和 49.8%（41.0-58.6%）。在性别和地区方面，牙龈炎的患病率存在显著差异：男性患病率高于女性，风险比为 1.04（95%CI，1.01-1.06）；城市地区的患病率低于农村地区，风险比为 0.90（95%CI，0.85-0.96）。