Mallinckrodt Institute of Radiology, Washington University School of Medicine, CB 8225, 510 S Kingshighway Blvd, St. Louis, MO 63110.
Department of Neurology, Washington University School of Medicine, St. Louis, MO.
AJR Am J Roentgenol. 2021 Mar;216(3):759-768. doi: 10.2214/AJR.20.23336. Epub 2021 Jan 21.
The purpose of this article is to summarize the role of molecular imaging of the brain by use of SPECT, FDG PET, and non-FDG PET radiotracers in epilepsy. Quantitative image analysis with PET and SPECT has increased the diagnostic utility of these modalities in localizing epileptogenic onset zones. A multi-modal platform approach integrating the functional imaging of PET and SPECT with the morphologic information from MRI in presurgical evaluation of epilepsy can greatly improve outcomes.
本文旨在总结 SPECT、FDG PET 和非 FDG PET 放射性示踪剂在癫痫中的脑分子成像作用。PET 和 SPECT 的定量图像分析提高了这些方法在定位致痫发作区中的诊断效用。在癫痫的术前评估中，将 PET 和 SPECT 的功能成像与 MRI 的形态信息相结合的多模态平台方法可以极大地改善结果。
