Department of Genetic Engineering & Biotechnology, Faculty of Biological Sciences, University of Chittagong , Chattogram, Bangladesh.
Department of Endocrinology, Chittagong Medical College , Chattogram, Bangladesh.
Glob Health Action. 2021 Jan 1;14(1):1872895. doi: 10.1080/16549716.2021.1872895.
: Diabetic individuals must adhere to their medications to control their glucose levels and prevent diabetes-related complications. However, there is limited evidence of medication adherence in patients with type 2 diabetes in Bangladesh. : We assessed the level of adherence and factors associated with low adherence to anti-diabetic medication among patients with type 2 diabetes at different health facilities in southern Bangladesh. : This cross-sectional study included 2,070 patients with type 2 diabetes who presented at five health facilities in the Chittagong Division between November 2018 and June 2019. We assessed medication adherence using a self-reported, structured, eight-item questionnaire and performed multiple logistic regression to investigate the factors associated with low medication adherence. : The overall prevalence of low medication adherence was 46.3% (95% CI: 41.4-55.8%) of our study population. Multiple logistic regression analysis revealed that males (OR: 1.37; 95% CI: 1.13-1.67), those with a family income of < 233 USD (OR: 1.54, 95% CI: 1.17-2.03), and those with a diabetic ulcer (OR: 1.42, 95% CI: 1.04-1.94) showed low adherence. Diabetic ulcers, retinopathy, and obesity were relatively more elevated among diabetic patients with low medication adherence. : Low medication adherence among patients with type 2 diabetes in southern Bangladesh is a key public health challenge. Factors such as male sex, low annual family income, and diabetic ulcers were associated with low medication adherence. Patient counseling and awareness programs may enhance medication adherence among people with type 2 diabetes. Our findings will help physicians and public health workers to develop targeted strategies to increase awareness of the same among their patients.
: 糖尿病患者必须坚持用药来控制血糖水平并预防糖尿病相关并发症。然而,在孟加拉国,关于 2 型糖尿病患者用药依从性的证据有限。: 我们评估了在孟加拉国南部不同医疗机构就诊的 2 型糖尿病患者的用药依从性水平及与低用药依从性相关的因素。: 这项横断面研究纳入了 2070 例 2018 年 11 月至 2019 年 6 月在吉大港分部的 5 家医疗机构就诊的 2 型糖尿病患者。我们使用自我报告的、结构化的 8 项问卷评估了用药依从性,并进行了多因素逻辑回归分析,以调查与低用药依从性相关的因素。: 我们研究人群中低用药依从性的总体患病率为 46.3%(95%CI:41.4-55.8%)。多因素逻辑回归分析显示,男性(OR:1.37;95%CI:1.13-1.67)、家庭收入<233 美元(OR:1.54,95%CI:1.17-2.03)和患有糖尿病溃疡(OR:1.42,95%CI:1.04-1.94)的患者依从性较低。低用药依从性的糖尿病患者中,糖尿病溃疡、视网膜病变和肥胖症的比例相对较高。: 孟加拉国南部 2 型糖尿病患者的低用药依从性是一个重大的公共卫生挑战。男性、低年收入和糖尿病溃疡等因素与低用药依从性相关。对患者进行咨询和开展相关教育项目可能会提高 2 型糖尿病患者的用药依从性。我们的研究结果将有助于医生和公共卫生工作者制定有针对性的策略,提高他们患者对这一问题的认识。