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孟加拉国 2 型糖尿病:基于患病率的疾病成本研究。

Type 2 diabetes mellitus in Bangladesh: a prevalence based cost-of-illness study.

机构信息

Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, 553 St. Kilda Rd., Level 4, Melbourne, VIC, 3004, Australia.

School of Population and Global Health, The University of Western Australia, Perth, Australia.

出版信息

BMC Health Serv Res. 2019 Aug 27;19(1):601. doi: 10.1186/s12913-019-4440-3.

Abstract

BACKGROUND

The economic burden of type 2 diabetes has not been adequately investigated in many low- and lower middle-income countries, including Bangladesh. The aim of this study was to estimate the cost-of-illness of type 2 diabetes and to find its determinants in Bangladesh.

METHODS

A cross-sectional study was conducted in 2017 to recruit 1253 participants with type 2 diabetes from six diabetes hospitals, providing primary to tertiary health care services, located in the northern and central regions of Bangladesh. A structured questionnaire was used for face-to-face interviewing to collect non-clinical data. Patients' medical records were reviewed for clinical data and hospital records were reviewed for hospitalisation data. Cost was calculated from the patient's perspective using a bottom-up methodology. The direct costs for each patient and indirect costs for each patient and their attendants were calculated. The micro-costing approach was used to calculate direct cost and the human capital approach was used to calculate indirect cost. Median regression analysis was performed to identify the determinants of average annual cost.

RESULTS

Among the participants, 54% were male. The mean (±SD) age was 55.1 ± 12.5 years and duration of diabetes was 10.7 ± 7.7 years. The average annual cost was US$864.7 per patient. Medicine cost accounted for 60.7% of the direct cost followed by a hospitalisation cost of 27.7%. The average annual cost for patients with hospitalisation was 4.2 times higher compared to those without hospitalisation. Being females, use of insulin, longer duration of diabetes, and presence of diabetes complications were significantly related to the average annual cost per patient.

CONCLUSIONS

The cost of diabetes care is considerably high in Bangladesh, and it is primarily driven by the medicine and hospitalisation costs. Optimisation of diabetes management by positive lifestyle changes is urgently required for prevention of comorbidities and complications, which in turn will reduce the cost.

摘要

背景

包括孟加拉国在内的许多低收入和中低收入国家,尚未充分研究 2 型糖尿病的经济负担。本研究旨在评估孟加拉国 2 型糖尿病的疾病经济负担并确定其决定因素。

方法

2017 年进行了一项横断面研究,从位于孟加拉国北部和中部的六家提供初级至三级医疗服务的糖尿病医院招募了 1253 名 2 型糖尿病患者。使用结构化问卷进行面对面访谈以收集非临床数据。查阅患者病历以获取临床数据,查阅医院记录以获取住院数据。采用自下而上的方法从患者角度计算成本。计算了每位患者的直接成本和每位患者及其陪护人员的间接成本。采用微观成本法计算直接成本,采用人力资本法计算间接成本。采用中位数回归分析确定平均年度费用的决定因素。

结果

参与者中 54%为男性。平均(±SD)年龄为 55.1±12.5 岁,糖尿病病程为 10.7±7.7 年。每位患者的平均年费用为 864.7 美元。药物费用占直接费用的 60.7%,其次是住院费用占 27.7%。与未住院的患者相比,住院患者的平均年费用高 4.2 倍。女性、使用胰岛素、糖尿病病程较长以及存在糖尿病并发症与每位患者的平均年度费用显著相关。

结论

在孟加拉国,糖尿病的治疗费用相当高,主要由药物和住院费用驱动。迫切需要通过积极的生活方式改变来优化糖尿病管理,以预防并发症和合并症,从而降低成本。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1755/6712789/e1311b459e6f/12913_2019_4440_Fig1_HTML.jpg

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