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食管癌患者术后出院后的补充肠内管饲营养。

Supplemental enteral tube feeding nutrition after hospital discharge of esophageal cancer patients who have undergone esophagectomy.

机构信息

Shizuoka Cancer Center, Division of Esophageal Surgery, 1007 Shimonagakubo, Nagaizumi-cho, Sunto-gun, Shizuoka, 411-8777, Japan.

Shizuoka Cancer Center, Nutrition Support Team, Sunto-gun, Japan.

出版信息

Esophagus. 2021 Jul;18(3):504-512. doi: 10.1007/s10388-020-00803-z. Epub 2021 Jan 21.

DOI:10.1007/s10388-020-00803-z
PMID:33475875
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8172505/
Abstract

BACKGROUND

After undergoing esophagectomy to treat esophageal cancer, there are changes in the normal intake patterns in most patients, with more than half found to have an inadequate oral intake at the time of their hospital discharge. However, the use of home supplemental enteral tube feeding nutrition after hospital discharge in esophagectomy patients has yet to be established. The aim of this study was to evaluate the feasibility of 90-day home supplemental enteral tube feeding nutrition in esophagectomy patients.

METHODS

This single-center, prospective, and single-arm study evaluated the feasibility of using supplemental tube feeding nutrition intervention for 90 days in esophageal cancer patients who have undergone esophagectomy.

RESULTS

This study enrolled 24 post-esophagectomy patients between February 2015 and September 2016. Twenty patients were administered 70% or more of the planned nutrient, with 83% of the patients completing the nutritional intervention procedure. There were no grade 3/4 adverse events observed, with a mean body weight change of - 7.6 ± 6.0%.

CONCLUSIONS

Our results showed that routine use of 90-day home supplemental enteral tube feeding nutrition after hospital discharge for esophagectomy patients was both feasible and acceptable.

TRIAL REGISTRATION

UMIN000016286.

摘要

背景

食管癌患者术后正常进食模式发生改变,大多数患者出院时存在经口摄食不足,超过半数患者出院后需要家庭肠内营养支持。本研究旨在评估食管癌患者出院后接受 90 天家庭肠内营养补充的可行性。

方法

本单中心前瞻性单臂研究纳入了 2015 年 2 月至 2016 年 9 月期间接受食管癌根治术的患者。

结果

共纳入 24 例食管癌术后患者,其中 20 例患者摄入了 70%及以上的计划营养量,83%的患者完成了营养干预。未观察到 3/4 级不良事件,平均体重变化为-7.6±6.0%。

结论

本研究结果表明,食管癌术后患者出院后常规使用 90 天家庭肠内营养补充是可行且可接受的。

试验注册

UMIN000016286。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cf85/8172505/3cf0277a7a1f/10388_2020_803_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cf85/8172505/97731eab7a5e/10388_2020_803_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cf85/8172505/38fdc5d7ec1f/10388_2020_803_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cf85/8172505/b257430c195f/10388_2020_803_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cf85/8172505/912702f0a3bd/10388_2020_803_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cf85/8172505/ee53d40210b0/10388_2020_803_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cf85/8172505/3cf0277a7a1f/10388_2020_803_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cf85/8172505/97731eab7a5e/10388_2020_803_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cf85/8172505/38fdc5d7ec1f/10388_2020_803_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cf85/8172505/b257430c195f/10388_2020_803_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cf85/8172505/912702f0a3bd/10388_2020_803_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cf85/8172505/ee53d40210b0/10388_2020_803_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cf85/8172505/3cf0277a7a1f/10388_2020_803_Fig6_HTML.jpg

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