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DBS 中纵向振动辅助插入的减摩机理。

Antifriction Mechanism of Longitudinal Vibration-Assisted Insertion in DBS.

机构信息

School of Mechanical Engineering, Shandong University, Jinan, 250061, China.

Key Laboratory of High Efficiency and Clean Mechanical Manufacture (Shandong University), Ministry of Education, Jinan, 250061, China.

出版信息

Ann Biomed Eng. 2021 Sep;49(9):2057-2065. doi: 10.1007/s10439-021-02730-1. Epub 2021 Jan 21.

DOI:10.1007/s10439-021-02730-1
PMID:33475894
Abstract

Deep brain stimulation (DBS) is an effective treatment for Parkinson's disease. The insertion of brain tissue is an important procedure that affects the whole operation and the sequela. During the insertion process, the friction between the tissue and the needle shaft is the main factor affecting the degree of tissue damage and the accuracy of target location. Vibration-assisted needle insertion has been shown to reduce friction during needle insertion into biological tissue. LuGre model is a friction model that includes coulomb friction and viscous friction between two contact surfaces and accurately describes the Stribeck effect. This paper studies the influence of longitudinal vibration on the friction force during needle insertion. Based on LuGre model, the influence of longitudinal vibration parameters on friction force is discussed. Through experiments on porcine brain tissue and gel phantom, the friction force during insertion and the positive pressure of tissue against the needle under different vibration parameters were investigated. The experiment showed that the vibration can change the friction force by affecting the equivalent friction coefficient and the positive pressure of tissue against the needle. The equivalent friction coefficient showed a specific trend with the change of vibration parameters, while the positive pressure does not change with the vibration parameters.

摘要

脑深部电刺激(DBS)是治疗帕金森病的有效方法。脑组织的插入是一个重要的过程,它会影响整个手术和后续结果。在插入过程中,组织和针轴之间的摩擦是影响组织损伤程度和目标位置准确性的主要因素。振动辅助针插入已被证明可以减少生物组织中针插入时的摩擦。LuGre 模型是一种摩擦模型,它包括两个接触表面之间的库仑摩擦和粘性摩擦,并准确描述了 Stribeck 效应。本文研究了纵向振动对针插入过程中摩擦力的影响。基于 LuGre 模型,讨论了纵向振动参数对摩擦力的影响。通过对猪脑组织和凝胶模型进行实验,研究了在不同振动参数下插入过程中的摩擦力和组织对针的正压力。实验表明,振动可以通过影响等效摩擦系数和组织对针的正压力来改变摩擦力。等效摩擦系数随着振动参数的变化呈现出特定的趋势,而正压力则不随振动参数的变化而变化。

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Antifriction Mechanism of Longitudinal Vibration-Assisted Insertion in DBS.DBS 中纵向振动辅助插入的减摩机理。
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本文引用的文献

1
Defining brain mechanical properties: effects of region, direction, and species.
Stapp Car Crash J. 2000 Nov;44:205-13. doi: 10.4271/2000-01-SC15.
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Shear Properties of Brain Tissue over a Frequency Range Relevant for Automotive Impact Situations: New Experimental Results.汽车碰撞情况下相关频率范围内脑组织的剪切特性:新的实验结果。
Stapp Car Crash J. 2004 Nov;48:239-58. doi: 10.4271/2004-22-0011.