Medical Scientist Training Program, Neurosciences Graduate Group, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Department of Biology, University of Pennsylvania, Philadelphia, PA 19104, USA.
Neuron. 2021 Jan 20;109(2):193-194. doi: 10.1016/j.neuron.2020.12.015.
In this issue of Neuron, Wang et al. employ an impressive multi-omics approach, including gene co-expression network analyses and drug repositioning, to normalize disease-disrupted gene modules and identify a therapeutically relevant driver of Alzheimer's disease.
在本期《神经元》杂志中，Wang 等人采用了令人印象深刻的多组学方法，包括基因共表达网络分析和药物重定位，以正常化疾病破坏的基因模块，并确定阿尔茨海默病的一个有治疗意义的驱动因素。
