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Vital Signs: Characteristics of Drug Overdose Deaths Involving Opioids and Stimulants - 24 States and the District of Columbia, January-June 2019.生命体征:涉及阿片类药物和兴奋剂的药物过量死亡特征 - 2019 年 1 月至 6 月,24 个州和哥伦比亚特区。
MMWR Morb Mortal Wkly Rep. 2020 Sep 4;69(35):1189-1197. doi: 10.15585/mmwr.mm6935a1.
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Rapid Techniques in Qualitative Research: A Critical Review of the Literature.快速定性研究技术:文献综述的批判性评价。
Qual Health Res. 2020 Aug;30(10):1596-1604. doi: 10.1177/1049732320921835.
3
Necropolitics in the "Compassionate" City: Care/Brutality in San Francisco.《“慈悲”之城的人口政治:旧金山的关怀/残忍》。
Med Anthropol. 2020 Nov-Dec;39(8):751-764. doi: 10.1080/01459740.2020.1753046. Epub 2020 May 4.
4
Motivations for crystal methamphetamine-opioid co-injection/co-use amongst community-recruited people who inject drugs: a qualitative study.动机研究:社区招募的注射吸毒者中同时使用冰毒和阿片类药物的原因:一项定性研究。
Harm Reduct J. 2020 Feb 27;17(1):14. doi: 10.1186/s12954-020-00360-9.
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Polysubstance use in rural West Virginia: Associations between latent classes of drug use, overdose, and take-home naloxone.西弗吉尼亚州农村地区的多物质使用:药物使用潜在类别、过量用药与纳洛酮带回家之间的关联
Int J Drug Policy. 2020 Feb;76:102642. doi: 10.1016/j.drugpo.2019.102642. Epub 2020 Jan 7.
6
The rise in non-fatal and fatal overdoses involving stimulants with and without opioids in the United States.美国涉及兴奋剂(有和没有阿片类药物)的非致命和致命过量用药的上升。
Addiction. 2020 May;115(5):946-958. doi: 10.1111/add.14878. Epub 2020 Jan 7.
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Polysubstance Use: A Broader Understanding of Substance Use During the Opioid Crisis.多物质使用:在阿片类药物危机期间对物质使用的更广泛理解。
Am J Public Health. 2020 Feb;110(2):244-250. doi: 10.2105/AJPH.2019.305412. Epub 2019 Dec 19.
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Association between methamphetamine use and retention among patients with opioid use disorders treated with buprenorphine.美沙酮使用与丁丙诺啡治疗阿片类药物使用障碍患者保留的关联。
J Subst Abuse Treat. 2020 Feb;109:80-85. doi: 10.1016/j.jsat.2019.10.005. Epub 2019 Nov 18.
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A nationally representative analysis of "twin epidemics": Rising rates of methamphetamine use among persons who use opioids.一项针对“双重流行”的全国代表性分析:阿片类药物使用者中使用冰毒的比例上升。
Drug Alcohol Depend. 2019 Nov 1;204:107592. doi: 10.1016/j.drugalcdep.2019.107592. Epub 2019 Sep 27.
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Increases in methamphetamine use among heroin treatment admissions in the United States, 2008-17.美国 2008-2017 年海洛因治疗入院者中甲基苯丙胺使用量增加。
Addiction. 2020 Feb;115(2):347-353. doi: 10.1111/add.14812. Epub 2019 Oct 24.

在俄勒冈州接受治疗的人群中,冰毒和阿片类药物的共同使用:对相关结构、社区和个体层面因素的定性研究。

Co-use of methamphetamine and opioids among people in treatment in Oregon: A qualitative examination of interrelated structural, community, and individual-level factors.

机构信息

Department of Anthropology, University of Maryland, 1111Woods Hall, 4302 Chapel Lane, College Park, MD 20742, USA.

Department of Anthropology, University of Maryland, 1111Woods Hall, 4302 Chapel Lane, College Park, MD 20742, USA.

出版信息

Int J Drug Policy. 2021 May;91:103098. doi: 10.1016/j.drugpo.2020.103098. Epub 2021 Jan 19.

DOI:10.1016/j.drugpo.2020.103098
PMID:33476863
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8648280/
Abstract

BACKGROUND

Rates of methamphetamine use and methamphetamine-related deaths have increased steadily in the United States in recent years. Methamphetamine is increasingly present in opioid-related deaths. An initial study of de-identified urine specimens (n = 102) collected at a drug treatment program between 2017 and 2018 indicated that 61% of specimens contained methamphetamine; of the specimens containing methamphetamine, people were, on average, five years younger than those who tested negative for methamphetamine; and non-fentanyl opioids were more than three times as common in methamphetamine positive specimens. The National Drug Early Warning System (NDEWS) Coordinating Center initiated a HotSpot Study to assess whether there was an emerging dynamic in the area, or if enhanced data collection could give insights into the co-use of methamphetamine and opioids.

METHODS

A qualitative study, grounded in principles of rapid ethnographic assessment and a social science/anthropological framework was conducted and used methodological complementarity to contextualize results from the initial urinalysis study. Targeted sampling was conducted at two treatment sites. Program staff and patients were recruited to participate in focus groups and semi-structured interviews to assess structural, community, and individual-level factors impacting methamphetamine and opioid co-use.

RESULTS

Within our broader framework of structural, community, and individual-level factors intersecting co-use, our data yielded three sub-themes: 1) the circulation of stigma regarding methamphetamine use was consistently described by both patients and staff and this intersected structural changes in treatment policy and suggested compounded stigma; 2) community-level factors and temporality were important for understanding patterns of methamphetamine use and for further interpreting the initial urinalysis; 3) patient rationales regarding the co-use of methamphetamine and opioids included strategies to mitigate the harms of heroin, as well as to detox or titrate the effects of heroin.

CONCLUSION AND IMPLICATIONS

Using an ethnographically-oriented and social science/anthropological approach and methodological complementarity to contextualize the prior urinalysis study demonstrates how behavioral variables cannot be abstracted from larger socio-structural and community contexts which impact people's decision-making process regarding co-use of methamphetamine and opioids. Further, by grounding our analysis in the meaning-centered and experiential narratives of people who use drugs, our research demonstrates the importance of considering the expertise of people who co-use opioids and methamphetamine as central for informing future sustainable program planning to address co-use that also accounts for the interrelationship between structural, community, and individual-level factors.

摘要

背景

近年来,美国的甲基苯丙胺使用和与甲基苯丙胺相关的死亡人数稳步上升。甲基苯丙胺在阿片类药物相关死亡中越来越常见。一项对 2017 年至 2018 年期间在一个戒毒治疗项目中收集的 102 份未经身份识别的尿液样本的初步研究表明,61%的样本含有甲基苯丙胺;在含有甲基苯丙胺的样本中,人的平均年龄比甲基苯丙胺检测呈阴性的人年轻五岁;在含有甲基苯丙胺的样本中,非芬太尼类阿片类药物的出现频率是检测呈阳性样本的三倍多。国家毒品预警系统(NDEWS)协调中心启动了一个热点研究,以评估该地区是否存在新的动态,或者加强数据收集是否可以深入了解甲基苯丙胺和阿片类药物的共同使用。

方法

一项基于快速人种学评估和社会科学/人类学框架的定性研究,并使用方法互补性来使初始尿液分析研究的结果背景化。在两个治疗地点进行了有针对性的抽样。招募项目工作人员和患者参加焦点小组和半结构化访谈,以评估影响甲基苯丙胺和阿片类药物共同使用的结构、社区和个人层面的因素。

结果

在我们结构、社区和个人层面因素相互交叉共同使用的更广泛框架内,我们的数据产生了三个子主题:1)患者和工作人员一致描述了关于甲基苯丙胺使用的污名循环,这与治疗政策的结构性变化相交织,并暗示了复合污名;2)社区层面的因素和时间因素对于理解甲基苯丙胺使用模式以及进一步解释初始尿液分析非常重要;3)患者关于甲基苯丙胺和阿片类药物共同使用的理由包括减轻海洛因危害的策略,以及戒除或调节海洛因的影响。

结论和影响

使用人种学为导向的和社会科学/人类学的方法以及方法互补性来使先前的尿液分析研究背景化,表明行为变量不能从影响人们关于甲基苯丙胺和阿片类药物共同使用决策过程的更大社会结构和社区背景中抽象出来。此外,通过将我们的分析建立在吸毒者的以意义为中心和经验性叙述的基础上,我们的研究表明,考虑到共同使用阿片类药物和甲基苯丙胺的人的专业知识的重要性,这是为解决共同使用问题提供信息的关键,同时也要考虑到结构、社区和个人层面因素之间的相互关系。