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利用第二代基于人工智能的数字药丸改善全球医疗保健并降低成本:市场颠覆者。

Improving Global Healthcare and Reducing Costs Using Second-Generation Artificial Intelligence-Based Digital Pills: A Market Disruptor.

机构信息

Department of Medicine, The Hebrew University of Jerusalem-Hadassah Medical Center, Jerusalem 12000, Israel.

出版信息

Int J Environ Res Public Health. 2021 Jan 19;18(2):811. doi: 10.3390/ijerph18020811.

Abstract

Improving global health requires making current and future drugs more effective and affordable. While healthcare systems around the world are faced with increasing costs, branded and generic drug companies are facing the challenge of creating market differentiators. Two of the problems associated with the partial or complete loss of response to chronic medications are a lack of adherence and compensatory responses to chronic drug administration, which leads to tolerance and loss of effectiveness. First-generation artificial intelligence (AI) systems do not address these needs and suffer from a low adoption rate by patients and clinicians. Second-generation AI systems are focused on a single subject and on improving patients' clinical outcomes. The digital pill, which combines a personalized second-generation AI system with a branded or generic drug, improves the patient response to drugs by increasing adherence and overcoming the loss of response to chronic medications. By improving the effectiveness of drugs, the digital pill reduces healthcare costs and increases end-user adoption. The digital pill also provides a market differentiator for branded and generic drug companies. Implementing the use of a digital pill is expected to reduce healthcare costs, providing advantages for all the players in the healthcare system including patients, clinicians, healthcare authorities, insurance companies, and drug manufacturers. The described business model for the digital pill is based on distributing the savings across all stakeholders, thereby enabling improved global health.

摘要

改善全球健康状况需要提高现有和未来药物的效果和可负担性。尽管全球各地的医疗保健系统都面临着成本不断上升的问题,但品牌和仿制药公司也面临着创造市场差异化的挑战。与慢性药物部分或完全失去反应相关的两个问题是缺乏依从性和对慢性药物治疗的代偿反应,这导致了耐受性和效果丧失。第一代人工智能 (AI) 系统无法满足这些需求,并且患者和临床医生的采用率低。第二代 AI 系统专注于单一主题,并致力于改善患者的临床结果。将个性化的第二代 AI 系统与品牌或仿制药相结合的数字药丸通过提高依从性和克服对慢性药物的反应丧失,改善了患者对药物的反应。通过提高药物的效果,数字药丸降低了医疗保健成本,并增加了最终用户的采用率。数字药丸还为品牌和仿制药公司提供了市场差异化的优势。预计使用数字药丸将降低医疗保健成本,为医疗保健系统中的所有参与者(包括患者、临床医生、医疗保健当局、保险公司和药品制造商)带来优势。所描述的数字药丸商业模式基于在所有利益相关者之间分配节省的成本,从而实现全球健康状况的改善。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fd95/7832873/c479fff78386/ijerph-18-00811-g001a.jpg

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