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地中海饮食对健康年轻男性精液参数的影响:一项随机对照试验。

Effects of Mediterranean diet on semen parameters in healthy young adults: a randomized controlled trial.

机构信息

Department of Advanced Medical and Surgical Sciences, University of Campania Luigi Vanvitelli, Naples, Italy.

Division of Endocrinology and Metabolic Diseases, University of Campania Luigi Vanvitelli, Naples, Italy.

出版信息

Minerva Endocrinol. 2020 Dec;45(4):280-287. doi: 10.23736/S0391-1977.20.03362-3.

DOI:10.23736/S0391-1977.20.03362-3
PMID:33478205
Abstract

BACKGROUND

Dietary regimens have so far been studied as possible determinants of semen quality and fertility. The aim of this study was to evaluate the effects of a Mediterranean diet, as compared with a low-fat diet, on seminal parameters of young healthy adults from southern Italy.

METHODS

In a randomized controlled trial, 160 young adults aged 18-30 years were assigned to Mediterranean diet (N.=80) or a low-fat diet (N.=80). The primary outcome measures were changes in semen parameters after six months.

RESULTS

Mean age of participants in the study was 24.7 years. There was no difference in baseline semen parameters of men randomized to Mediterranean diet or low-fat diet. After the entire follow-up, participants in both groups showed a significant increase in sperm concentration and sperm total count, with significant differences favoring the Mediterranean diet group (sperm concentration, 1.93 M/mL 95% CI [1.22 to 3.64], P=0.027; total sperm count 8.02 M 95% CI [1.51 to 15.45], P=0.035). No differences in other semen parameters were found between groups.

CONCLUSIONS

In healthy young adults, the consumption of Mediterranean diet was associated with an improvement of both sperm concentration and total count, as compared with a low-fat diet.

摘要

背景

饮食方案一直被研究作为精液质量和生育能力的可能决定因素。本研究旨在评估与低脂饮食相比,地中海饮食对来自意大利南部的年轻健康成年人的精液参数的影响。

方法

在一项随机对照试验中,将 160 名年龄在 18-30 岁的年轻成年人随机分为地中海饮食组(N=80)或低脂饮食组(N=80)。主要观察指标是 6 个月后精液参数的变化。

结果

研究参与者的平均年龄为 24.7 岁。随机分配到地中海饮食或低脂饮食组的男性在基线精液参数方面没有差异。在整个随访期间,两组参与者的精子浓度和总精子计数均显著增加,地中海饮食组的差异更显著(精子浓度,1.93M/ml 95%CI[1.22 至 3.64],P=0.027;总精子数 8.02M 95%CI[1.51 至 15.45],P=0.035)。两组之间其他精液参数没有差异。

结论

在健康的年轻成年人中,与低脂饮食相比,地中海饮食的摄入与精子浓度和总计数的提高有关。

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