Department of Respiratory Medicine, The Affiliated Brain Hospital of Nanjing Medical University, Nanjing, Jiangsu, China.
Clinical Center of Nanjing Respiratory Diseases and Imaging, Nanjing, Jiangsu, China.
Technol Cancer Res Treat. 2021 Jan-Dec;20:1533033821989992. doi: 10.1177/1533033821989992.
X-ray guided transbronchial ultrasound-guided transbronchial lung biopsy (EBUS-TBLB) can improve the diagnostic yield of peripheral pulmonary lesions (PPLs), but it needs special requirements. The purpose of this study was to investigate the clinical value of virtual bronchoscopy navigation (VBN) combined with EBUS-TBLB in the diagnosis of PPLs without X-ray guidance.
The 105 patients with PPLs underwent EBUS-TBLB with or without VBN randomly. The diagnostic yield, the operation time and complications were evaluated in the 2 groups.
No significant difference was found between the VBN+EBUS group and the EBUS group (76.0% vs. 65.5%, = 0.287). The operation time of VBN+EBUS group was significantly shorter than that of EBUS group (20.6 ± 12.8 min vs. 28.6 ± 14.3 min, = 0.023). No severe procedure related complications occurred.
VBN can shorten the operation time. The combination of VBN and EBUS-TBLB is a safe and effective diagnosis technique for PPLs.
X 射线引导下经支气管超声引导经支气管肺活检（EBUS-TBLB）可以提高周围性肺病变（PPL）的诊断率，但需要特殊要求。本研究旨在探讨虚拟支气管镜导航（VBN）联合 EBUS-TBLB 在无 X 射线引导下诊断 PPL 的临床价值。
将 105 例 PPL 患者随机分为 VBN+EBUS 组和 EBUS 组，分别采用 VBN+EBUS 或单纯 EBUS-TBLB 进行诊断。评估两组的诊断率、手术时间和并发症。
VBN+EBUS 组与 EBUS 组的诊断率差异无统计学意义（76.0%比 65.5%， = 0.287）。VBN+EBUS 组的手术时间明显短于 EBUS 组（20.6±12.8 min 比 28.6±14.3 min， = 0.023）。两组均未发生严重的与操作相关的并发症。
VBN 可缩短手术时间。VBN 联合 EBUS-TBLB 是一种安全有效的 PPL 诊断技术。
