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中链甘油三酯和中长链甘油三酯:代谢、生产、对健康的影响及其应用——综述

Medium chain triglyceride and medium-and long chain triglyceride: metabolism, production, health impacts and its applications - a review.

作者信息

Lee Yee-Ying, Tang Teck-Kim, Chan Eng-Seng, Phuah Eng-Tong, Lai Oi-Ming, Tan Chin-Ping, Wang Yong, Ab Karim Nur Azwani, Mat Dian Noorlida Habi, Tan Joo Shun

机构信息

School of Science, Monash University Malaysia, Bandar Sunway, Selangor, Malaysia.

Monash Industry Palm Oil Research and Education Platform, Monash University Malaysia, Bandar Sunway, Selangor, Malaysia.

出版信息

Crit Rev Food Sci Nutr. 2022;62(15):4169-4185. doi: 10.1080/10408398.2021.1873729. Epub 2021 Jan 22.

Abstract

Structured lipid is a type of modified form of lipid that is "fabricated" with the purpose to improve the nutritional and functional properties of conventional fats and oils derived from animal and plant sources. Such healthier choice of lipid received escalating attention from the public for its capability to manage the rising prevalence of metabolic syndrome. Of which, medium-chain triacylglycerol (MCT) and medium-and long-chain triacylglycerol (MLCT) are the few examples of the "new generation" custom-made healthful lipids which are mainly composed of medium chain fatty acid (MCFA). MCT is made up exclusively of MCFA whereas MLCT contains a mixture of MCFA and long chain fatty acid (LCFA), respectively. Attributed by the unique metabolism of MCFA which is rapidly metabolized by the body, MCFA and MCT showed to acquire multiple physiological and functional properties in managing and reversing certain health disorders. Several chemically or enzymatically oils and fats modification processes catalyzed by a biological or chemical catalyst such as acidolysis, interesterification and esterification are adopted to synthesis MCT and MLCT. With their purported health benefits, MCT and MLCT are widely being used as nutraceutical in food and pharmaceutical sectors. This article aims to provide a comprehensive review on MCT and MLCT, with an emphasis on the basic understanding of its structures, properties, unique metabolism; the current status of the touted health benefits; latest routes of production; its up-to-date applications in the different food systems; relevant patents filed and its drawbacks.

摘要

结构化脂质是一种脂质的改性形式,其“制造”目的是改善来自动植物来源的传统油脂的营养和功能特性。这种更健康的脂质选择因其能够应对代谢综合征患病率不断上升的问题而受到公众越来越多的关注。其中,中链甘油三酯(MCT)和中长链甘油三酯(MLCT)是“新一代”定制健康脂质的少数例子,它们主要由中链脂肪酸(MCFA)组成。MCT仅由MCFA组成,而MLCT分别含有MCFA和长链脂肪酸(LCFA)的混合物。由于MCFA独特的代谢方式,即能被身体快速代谢,MCFA和MCT在管理和逆转某些健康问题方面表现出具有多种生理和功能特性。通过生物或化学催化剂催化的几种化学或酶促油脂改性过程,如酸解、酯交换和酯化反应,被用于合成MCT和MLCT。由于其宣称的健康益处,MCT和MLCT在食品和制药行业被广泛用作营养保健品。本文旨在对MCT和MLCT进行全面综述,重点是对其结构、性质、独特代谢的基本理解;所宣称的健康益处的现状;最新的生产路线;其在不同食品体系中的最新应用;已提交的相关专利及其缺点。

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