From the Division of Pain Medicine, Department of Physical Medicine and Rehabilitation, Science Health University, Şişli Hamidiye Etfal Training and Research Hospital, Istanbul, Turkey (TŞ); Department of Physical Medicine and Rehabilitation, Science Health University, Şişli Hamidiye Etfal Training and Research Hospital, Istanbul, Turkey (AA, BK); Physical Medicine and Rehabilitation Department, Marmara University Medical Faculty, Istanbul, Turkey (KG-A); Department of Neurosurgery, Science Health University, Şişli Hamidiye Etfal Training and Research Hospital, Istanbul, Turkey (CA); and Department of Orthopedics and Traumatology, Science Health University, Şişli Hamidiye Etfal Training and Research Hospital, Istanbul, Turkey (HMÖ).
Am J Phys Med Rehabil. 2021 Apr 1;100(4):307-312. doi: 10.1097/PHM.0000000000001699.
The clinical manifestations of COVID-19 range from mild symptoms to severe pneumonia and severe organ damage. When evaluated specifically for pain, the data so far have shown that myalgia, headache, and chest pain can be seen in patients at varying rates; myalgia and headache, especially, are among the initial symptoms.
This retrospective chart review, followed by a descriptive survey design study, was carried out by examining patients afflicted with COVID-19. After discharge, patients were asked about the severity and the body region of their pain, their use of analgesics, their mood and mental health, and their overall quality of life.
A total of 206 patients with a mean age of 56.24 ± 16.99 yrs were included in the study. Pain during COVID-19 was found to be higher compared with the preinfectious and postinfectious states. The most frequent painful areas were reported to be the neck and back before the infection, whereas the head and limbs during the infection. The most frequently used analgesic during infection was paracetamol. There was no relationship between the patients' pain and anxiety and depression; the quality of life was found to be worse in patients with persistent pain.
This study showed that the head and limbs were the most common painful body regions during COVID-19. It was also found that pain can continue in the postinfection period.
COVID-19 的临床表现从轻微症状到严重肺炎和严重器官损伤不等。当专门评估疼痛时，迄今为止的数据表明，患者的肌肉疼痛、头痛和胸痛发生率不同；特别是肌肉疼痛和头痛是最初的症状之一。
这项回顾性图表审查，随后进行描述性调查设计研究，通过检查感染 COVID-19 的患者来进行。出院后，患者被询问疼痛的严重程度和身体部位、他们使用的镇痛药、他们的情绪和心理健康以及他们的整体生活质量。
共有 206 名平均年龄为 56.24 ± 16.99 岁的患者纳入研究。与感染前和感染后相比，COVID-19 期间的疼痛更高。感染前报告的最常见疼痛部位是颈部和背部，而感染期间是头部和四肢。感染期间最常使用的镇痛药是对乙酰氨基酚。患者的疼痛与焦虑和抑郁之间没有关系；持续疼痛的患者生活质量较差。
这项研究表明，头部和四肢是 COVID-19 期间最常见的疼痛部位。还发现疼痛在感染后仍会持续。
