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腹膜外法国式安行剖宫产术与腹腔内米氏剖宫产术比较,可改善疼痛评分,更快实现产妇自主活动:一项前瞻性随机对照试验。

The extraperitoneal French AmbUlatory cesarean section technique leads to improved pain scores and a faster maternal autonomy compared with the intraperitoneal Misgav Ladach technique: A prospective randomized controlled trial.

机构信息

Obstetrics and Gynecology Department, Mongi Slim University Hospital, La Marsa, Tunisia.

Faculty of Medicine, University Tunis El Manar, Tunis, Tunisia.

出版信息

PLoS One. 2021 Jan 22;16(1):e0245645. doi: 10.1371/journal.pone.0245645. eCollection 2021.

Abstract

OBJECTIVE

To determine whether the French AmbUlatory Cesarean Section (FAUCS) technique reduces postoperative pain and promotes maternal autonomy compared with the Misgav Ladach cesarean section (MLCS) technique in elective conditions.

STUDY DESIGN

One hundred pregnant women were randomly, but in a non-blinded manner, assigned to undergo FAUCS or MLCS. The primary outcome was a postoperative mean pain score (PMPS), and secondary outcomes were a combined pain/medication score, time to regain autonomy, surgical duration, calculated blood loss, surgical complications, and neonatal outcome.

RESULTS

Women in the FAUCS group experienced less pain than those in the MLCS group (PMPS = 1.87 [1.04-2.41] vs. 2.93 [2.46-3.75], respectively; p < 0.001). Six hours after surgery, the combined pain/medication score for FAUCS patients was 33% lower than that for MLCS patients (p < 0.001). FAUCS patients more rapidly regained autonomy, with 94% reaching autonomy within 12 h vs. 4% of MLCS patients (p < 0.001). There were no differences in maternal surgical or neonatal complications between groups.

CONCLUSIONS

Our results indicate that FAUCS can reduce postoperative pain and accelerate recovery, suggesting that this technique might be superior to MLCS and should be more widely used. One potentially key difference between FAUCS and MLCS is that MLCS includes 100 mcg spinal morphine anesthesia in addition to the same anesthesia used by FAUCS. Any interpretation of apparent differences must take the presence/absence of morphine into account.

摘要

目的

与Misgav Ladach 剖宫产术(MLCS)相比,确定法国门诊剖宫产术(FAUCS)技术是否能降低择期剖宫产术后疼痛并促进产妇自主性。

研究设计

100 名孕妇被随机(但非盲法)分配至 FAUCS 组或 MLCS 组。主要结局为术后平均疼痛评分(PMPS),次要结局为疼痛/药物联合评分、恢复自主性时间、手术时间、估计失血量、手术并发症和新生儿结局。

结果

FAUCS 组的产妇疼痛程度低于 MLCS 组(PMPS=1.87[1.04-2.41] vs. 2.93[2.46-3.75];p<0.001)。术后 6 小时,FAUCS 组的疼痛/药物联合评分比 MLCS 组低 33%(p<0.001)。FAUCS 组更快恢复自主性,94%的产妇在 12 小时内达到自主性,而 MLCS 组仅 4%的产妇达到(p<0.001)。两组产妇的手术或新生儿并发症无差异。

结论

我们的研究结果表明,FAUCS 可降低术后疼痛并加速恢复,提示该技术可能优于 MLCS,应更广泛应用。FAUCS 与 MLCS 的一个潜在关键差异在于,MLCS 除了 FAUCS 所用的相同麻醉外,还包括 100mcg 脊髓吗啡麻醉。对明显差异的任何解释都必须考虑吗啡的存在/缺失。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6fc8/7822305/81bbf37a50cf/pone.0245645.g001.jpg

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