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基于细胞和分子技术的新冠病毒综合与转化病理生物学

Comprehensive and translational pathobiology of COVID-19 based on cellular and molecular techniques.

作者信息

Samadani Ali Akbar, Vahidi Sogand, Babaei Kosar, Norollahi Seyedeh Elham, Delpasand Kourosh, Gharakhyli Elaheh Asghari

机构信息

Guilan Road Trauma Research Center, Trauma Institute, Guilan University of Medical Sciences, Rasht, Iran.

Medical Biology Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran.

出版信息

Pract Lab Med. 2025 Aug 11;46:e00497. doi: 10.1016/j.plabm.2025.e00497. eCollection 2025 Sep.

Abstract

The biggest health issue in the world right now is the COVID-19 pandemic. This outbreak has caused a lot more people to be hospitalized for pneumonia and serious health problems, leading to many deaths. This report talks about many studies that showed the causes and how common COVID-19 is, as well as how to diagnose it in clinics and labs, and how to prevent and control it. These studies are very important and directly related to COVID-19 to help manage the current public emergency. Many parts of this dangerous disease, like how it spreads, how to diagnose it, how it infects people, and how to treat it, are still not well understood. It's important that to prevent, diagnose, and treat COVID-19 well, we need research at the molecular and clinical levels, along with public health measures and medical treatments. Clearly, new treatments like mesenchymal stem cell therapy have shown great promise in this area. Here, we will talk about and show the advanced lab methods used to understand how COVID-19 spreads, how it is diagnosed, and how it can be treated.

摘要

目前全球最大的健康问题是新冠疫情。此次疫情导致更多人因肺炎和严重健康问题住院,造成许多人死亡。本报告探讨了多项研究,这些研究揭示了新冠病毒的成因、流行程度,以及在诊所和实验室中的诊断方法,还有预防和控制措施。这些研究非常重要,与新冠疫情直接相关,有助于应对当前的公共卫生紧急情况。这种危险疾病的许多方面,如传播方式、诊断方法、感染途径和治疗手段,仍未被充分了解。为了做好新冠疫情的预防、诊断和治疗工作,分子和临床层面的研究以及公共卫生措施和医学治疗都很重要。显然,间充质干细胞疗法等新疗法在这一领域已显示出巨大潜力。在此,我们将探讨并展示用于了解新冠病毒传播、诊断和治疗的先进实验室方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b87d/12391832/7421d8f99d66/ga1.jpg

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