Department of Otolaryngology, Head and Neck Surgery, Kaplan Medical Center, Rehovot, Israel; Hebrew University, Hadassah Medical School, Jerusalem, Israel.
Department of Otolaryngology, Head and Neck Surgery, Kaplan Medical Center, Rehovot, Israel.
Am J Otolaryngol. 2021 May-Jun;42(3):102902. doi: 10.1016/j.amjoto.2021.102902. Epub 2021 Jan 16.
Thyroglossal duct cyst (TGDC) may appear in all age groups. The impact of age on surgical outcome has been reported with conflicting results. The aim of the study was to evaluate different risk factors for surgical success according to stratified age groups.
A single center retrospective study. All patients who underwent a Sistrunk procedure between 2004 and 2018 were enrolled. Data included demographics, pre-operative presentation, intra\postoperative complications and surgical failures. Population groups were divided into adults (≥18 years), older children (OC, 3-18 years) and toddlers (<3 years).
A total of 109 patients were included: 55 adults (50.5%), 36 OC (33%) and 18 toddlers (16.5%). The adult group demonstrated a significant lower rate of surgical failures when compared to the toddler (3.6%, vs. 38.9%, P < 0.001, respectively) and the OC group (3.6%, vs 16.7%, P = 0.032, respectively). A borderline significance was found when comparing surgical failure rates among toddlers and OC (38.9% vs.16.7%, P = 0.07, respectively). Post-operative complications were associated with surgical failures among toddlers (P = 0.045) and OC (P = 0.016), but not adults. Pre-operative infection and admission were significantly associated with failure in the OC group.
Surgical failures following Sistrunk procedures and their associated risk factors vary between age groups. Familiarity with these rates and associations can contribute to better decision making in managing TGDC patients.
甲状舌管囊肿（TGDC）可发生于各年龄段。年龄对手术结果的影响已有报道，但结果相互矛盾。本研究旨在根据分层年龄组评估手术成功的不同危险因素。
单中心回顾性研究。纳入 2004 年至 2018 年间行 Sistrunk 手术的所有患者。数据包括人口统计学、术前表现、围手术期并发症和手术失败。人群分为成人（≥18 岁）、大龄儿童（3-18 岁）和幼儿（<3 岁）。
共纳入 109 例患者：成人 55 例（50.5%），大龄儿童 36 例（33%），幼儿 18 例（16.5%）。与幼儿（3.6%，vs.38.9%，P<0.001）和大龄儿童（3.6%，vs.16.7%，P=0.032）相比，成人组手术失败率显著较低。幼儿和大龄儿童之间的手术失败率比较有边界意义（38.9%vs.16.7%，P=0.07）。术后并发症与幼儿（P=0.045）和大龄儿童（P=0.016）的手术失败相关，但与成人无关。术前感染和住院与大龄儿童组的失败显著相关。
Sistrunk 手术后的手术失败及其相关危险因素在不同年龄组之间有所不同。熟悉这些发生率和相关性有助于更好地决策治疗 TGDC 患者。
