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980nm 半导体激光治疗根尖周炎根管治疗术后疼痛的随机临床试验

Effect of a 980-nm diode laser on post-operative pain after endodontic treatment in teeth with apical periodontitis: a randomized clinical trial.

机构信息

Department of Endodontics, Faculty of Dentistry, Biruni University, Istanbul, Turkey.

出版信息

BMC Oral Health. 2021 Jan 22;21(1):41. doi: 10.1186/s12903-021-01401-w.

DOI:10.1186/s12903-021-01401-w
PMID:33482797
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7821509/
Abstract

BACKGROUND

This study aimed to assess the effect of a 980-nm diode laser following chemomechanical root canal preparation on the severity of post-operative pain (PP) after root canal treatment (RCT).

METHODS

This study included asymptomatic, single-rooted teeth with a periapical index (PAI) score of 3 or 4. All the patients received RCT, including dressing with calcium hydroxide (Ca(OH)), during two visits. The patients were randomly divided into two groups (n:30): a control group, in which the final irrigation was performed using 5 ml of 2.5% sodium hypochlorite (NaOCI), followed by 5 ml of 17% and ethylenediaminetetraacetic acid (EDTA) and 5 ml of distilled water, and a laser group, in which the root canals were irradiated using a 980-nm diode laser after the final irrigation at both visits. The pain levels after both visits were evaluated using a visual analogue scale (VAS) after 8 h, 24 h, 48 h and 7 d. In addition, the time intervals to medication intake were recorded. The collected data were statistically analysed using the chi-square and Mann-Whitney U test (p < 0.05).

RESULTS

The average pain level in the control group 24 h after the first visit was significantly higher than that in the laser group (p < 0.05). The average pain level 24 h and 48 h after the second visit was significantly higher in the control group (p < 0.05). The levels of PP 24 h after the first visit were higher than those after the second visit only in the control group (p < 0.05). After the first visit, analgesic use in the control group was significantly higher after 8 h (40%) and 24 h (23%) as compared with that in the laser group (p < 0.05).

CONCLUSIONS

Root canal irradiation with a diode laser may reduce PP after RCT in single-rooted teeth with a PAI score of 3 or 4.

TRIAL REGISTRATION

Effect of the Diode Laser on Post-operative Pain After Endodontic Treatment in Teeth with Apical Periodontitis: NCT04486196. Registered 24 July 2020-Retrospectively registered, http://clinicaltrials.gov/ct2/show/NCT04486196.

摘要

背景

本研究旨在评估 980nm 二极管激光在根管化学机械预备后对根管治疗(RCT)后术后疼痛(PP)严重程度的影响。

方法

本研究纳入无症状、根尖指数(PAI)评分为 3 或 4 的单根牙。所有患者均接受了 RCT,包括在两次就诊时用氢氧化钙(Ca(OH))进行根管封药。患者被随机分为两组(n:30):对照组,最后冲洗用 5ml 2.5%次氯酸钠(NaOCI),再用 5ml 17%和乙二胺四乙酸(EDTA),5ml 蒸馏水;激光组,在两次就诊的最后冲洗后,用 980nm 二极管激光照射根管。在 8 小时、24 小时、48 小时和 7 天时,使用视觉模拟量表(VAS)评估两次就诊后的疼痛水平。此外,记录服用药物的时间间隔。使用卡方检验和曼-惠特尼 U 检验(p < 0.05)对收集的数据进行统计学分析。

结果

首次就诊后 24 小时,对照组的平均疼痛水平显著高于激光组(p < 0.05)。第二次就诊后 24 小时和 48 小时,对照组的平均疼痛水平显著升高(p < 0.05)。首次就诊后 24 小时,对照组的疼痛水平高于第二次就诊(p < 0.05)。首次就诊后 8 小时(40%)和 24 小时(23%),对照组的镇痛药物使用率显著高于激光组(p < 0.05)。

结论

对于根尖指数为 3 或 4 的单根牙,根管内照射二极管激光可能会降低 RCT 后的 PP。

试验注册

二极管激光对根尖周炎牙齿根管治疗后术后疼痛的影响:NCT04486196。2020 年 7 月 24 日注册-回顾性注册,http://clinicaltrials.gov/ct2/show/NCT04486196。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d54/7821509/82dc9833846f/12903_2021_1401_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d54/7821509/82dc9833846f/12903_2021_1401_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d54/7821509/82dc9833846f/12903_2021_1401_Fig1_HTML.jpg

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