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超声联合激光冲洗在根管治疗术后疼痛的随机临床试验。

Postoperative pain after ultrasonically and laser-activated irrigation during root canal treatment: a randomized clinical trial.

机构信息

Department of Oral Health Sciences, Section of Endodontology, Ghent University, Ghent, Belgium.

出版信息

Int Endod J. 2021 Jul;54(7):1037-1050. doi: 10.1111/iej.13500. Epub 2021 Mar 9.

Abstract

AIM

To compare the intensity of postoperative pain after primary root canal treatment of asymptomatic teeth when using ultrasonically (UAI) or laser-activated irrigation (LAI).

METHODOLOGY

In this superiority randomized clinical trial (ClinicalTrials.gov ID: NCT03981237) with parallel design, fifty-six patients with an asymptomatic tooth in need of primary root canal treatment were enrolled. After chemo-mechanical canal preparation using rotary instruments and NaOCl irrigation, teeth were randomly assigned to two groups and patients were blinded to the final irrigation protocol. In the UAI group (n = 28), 60s activation with an Irrisafe tip was done per canal. In the LAI group (n = 28), NaOCl was activated with a pulsed Er:YAG (2940 nm) laser, equipped with a conical tip, with settings of 50 µs, 20 mJ at 15 Hz for 60 s. Patients recorded their pain intensity 6, 24, 48 and 72 h after treatment on a 100 mm visual analogue scale (VAS), as well as their analgesic consumption. Pain levels and incidence were compared across groups using the Mann-Whitney U-test and chi-square test.

RESULTS

Overall, mean postoperative pain intensity was low, with the majority of patients having no or minimal pain 24 h postoperatively. At 6 h postoperatively, pain intensity and incidence were significantly higher in the UAI group compared to the LAI group (P < 0.05). For the other time intervals, no significant differences in postoperative pain incidence or intensity were found. The frequency of analgesic intake did not differ significantly between the two groups. Neither of the activation methods resulted in any adverse effects.

CONCLUSIONS

Ultrasonically and laser-activated irrigation resulted in low and comparable levels of postoperative pain in asymptomatic patients receiving primary root canal treatment.

摘要

目的

比较超声(UAI)或激光激活冲洗(LAI)在对无症状牙齿进行初次根管治疗后术后疼痛强度。

方法

这是一项具有平行设计的优效性随机临床试验(ClinicalTrials.gov 注册号:NCT03981237),共纳入 56 名需要初次根管治疗的无症状牙齿患者。使用旋转器械和 NaOCl 冲洗进行化学机械根管预备后,将牙齿随机分为两组,患者对最终冲洗方案设盲。在 UAI 组(n=28),每根管进行 60s 的 Irrisafe 尖端激活。在 LAI 组(n=28),用配备锥形尖端的脉冲 Er:YAG(2940nm)激光对 NaOCl 进行激活,设置为 50µs、20mJ、15Hz 共 60s。治疗后 6、24、48 和 72h,患者使用 100mm 视觉模拟量表(VAS)记录疼痛强度,并记录镇痛药的使用情况。使用 Mann-Whitney U 检验和卡方检验比较组间疼痛水平和发生率。

结果

总体而言,术后疼痛强度较低,大多数患者在术后 24h 内无疼痛或仅有轻微疼痛。术后 6h,UAI 组的疼痛强度和发生率明显高于 LAI 组(P<0.05)。对于其他时间间隔,术后疼痛发生率或强度无显著差异。两组镇痛药的使用频率无显著差异。两种激活方法均未导致任何不良反应。

结论

在接受初次根管治疗的无症状患者中,超声和激光激活冲洗均导致术后疼痛强度低且相似。

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